Affinity DataIC50: 0.0310nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0440nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Agonist activity at VDR (unknown origin) expressed in HEK293 cells cotransfected with NCoR assessed as decrease in NCoR recruitment by two-hybrid ass...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Agonist activity at VDR (unknown origin) expressed in HEK293 cells cotransfected with NCoR assessed as decrease in NCoR recruitment by two-hybrid ass...More data for this Ligand-Target Pair
Affinity DataIC50: 0.110nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.160nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from recombinant human VDR ligand binding domainMore data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.470nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 0.960nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human N-terminal FLAG/His-tagged KDM5B (2 to 751 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK...More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against neutral endopeptidase (NEP)prepared from microsomal fractions of rat small intestineMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-21)K4(Me3)-GGK(Bi...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from recombinant human VDR ligand binding domainMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of full-length human N-terminal FLAG/His-tagged KDM5C (2 to 1560 residues) expressed in baculovirus infected Sf9 insect cells using H3(1-2...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dainippon Pharmaceutical
Curated by ChEMBL
Dainippon Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:Inhibitory concentration against inducible nitric acid synthaseMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dainippon Pharmaceutical
Curated by ChEMBL
Dainippon Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibitory concentration against inducible nitric acid synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from recombinant human VDR ligand binding domainMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Dainippon Pharmaceutical
Curated by ChEMBL
Dainippon Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration against inducible nitric acid synthaseMore data for this Ligand-Target Pair