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Found 234 with Last Name = 'bühler' and Initial = 's'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343508(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  2nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343492((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  2nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343505((S)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...)
Affinity DataIC50:  3nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343506((R)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...)
Affinity DataIC50:  4nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343507(4-(4-(4-Fluorophenyl)-2-(isopropylthio)-1H-imidazo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50251985(4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  5nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343505((S)-4-(4-(4-fluorophenyl)-2-(isopropylsulfinyl)-1H...)
Affinity DataIC50:  6nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50330167(2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-(met...)
Affinity DataIC50:  9nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343504((R)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropy...)
Affinity DataIC50:  11nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343502((R)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  11nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343493((R)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  12nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343487((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  12nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343489(CHEMBL1773502 | N-Cyclohexyl-4-(4-(4-fluorophenyl)...)
Affinity DataIC50:  12nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM13336(4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343485(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  17nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343488(CHEMBL1773421 | rac-N-Cyclohexyl-4-(4-(4-fluorophe...)
Affinity DataIC50:  18nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343486(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  19nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343503((S)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(isopropy...)
Affinity DataIC50:  21nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343492((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  24nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343479(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  25nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343501(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  26nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50251974(CHEMBL482086 | Cyclohexyl-{4-[4-(4-fluoro-phenyl)-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343485(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  27nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343491((R)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(methylsu...)
Affinity DataIC50:  29nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343483(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  31nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343490((S)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(methylsu...)
Affinity DataIC50:  34nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343487((S)-4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H-im...)
Affinity DataIC50:  34nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343482(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  36nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343498(CHEMBL1773425 | N-(4-(4-(4-Fluorophenyl)-2-(methyl...)
Affinity DataIC50:  37nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343484(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  40nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343478(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  45nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50130656(CHEMBL321415 | {4-[5-(4-Fluoro-phenyl)-2-methylsul...)
Affinity DataIC50:  50nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343501(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  50nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343490((S)-N-cyclohexyl-4-(4-(4-fluorophenyl)-2-(methylsu...)
Affinity DataIC50:  50nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343482(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  61nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50130657(CHEMBL109331 | {4-[5-(4-Fluoro-phenyl)-2-methylsul...)
Affinity DataIC50:  65nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343494((S)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50:  69nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343495((R)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50:  77nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50031048(3-(4-(trifluoromethyl)phenyl)-5H-indeno[1,2-c]pyri...)
Affinity DataIC50:  90nMAssay Description:Ability to inhibit Monoamine oxidase B enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343478(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  95nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343507(4-(4-(4-Fluorophenyl)-2-(isopropylthio)-1H-imidazo...)
Affinity DataIC50:  120nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343508(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  130nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343494((S)-2-(4-fluorophenyl)-N-(4-(4-(4-fluorophenyl)-2-...)
Affinity DataIC50:  141nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343485(4-(4-(4-fluorophenyl)-2-((S)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  150nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343497((R)-N-(4-(4-(4-fluorophenyl)-2-(methylsulfinyl)-1H...)
Affinity DataIC50:  161nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343481(4-(4-(4-fluorophenyl)-2-((R)-methylsulfinyl)-1H-im...)
Affinity DataIC50:  168nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50251974(CHEMBL482086 | Cyclohexyl-{4-[4-(4-fluoro-phenyl)-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50343484(4-(4-(4-Fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  180nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50251985(4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5...)
Affinity DataIC50:  180nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as suppression of LPS-induced TNF-alpha release by immunosorbent non-radioactive enzyme as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-University Tu£Bingen

Curated by ChEMBL
LigandPNGBDBM50130648(CHEMBL432798 | N-{4-[5-(4-Fluoro-phenyl)-3-methyl-...)
Affinity DataIC50:  188nMAssay Description:Inhibition of p38 alpha MAPK in human whole blood assessed as phosphorylation of ATF-2 by immunosorbent non-radioactive enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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