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Found 18 with Last Name = 'bürzle' and Initial = 'm'
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327886((1R,2S,5S,6S)-3-azabicyclo[3.1.0]hexane-2,6-dicarb...)
Affinity DataKi:  1.60E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50197105((2S,1'S,2'R)-2-(2'-Carboxycyclobutyl)glycine | CHE...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327885((2S,3S)-pyrrolidine-2,3-dicarboxylic acid | CHEMBL...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50180145((1R,4S,5R,6S)-3-azabicyclo[3.3.0]octane-4,6-dicarb...)
Affinity DataKi:  5.20E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327884((2S,3S)-2-amino-3-(3-(4-(trifluoromethyl)benzamido...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327884((2S,3S)-2-amino-3-(3-(4-(trifluoromethyl)benzamido...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human EAAC1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50417031(CHEMBL2062159 | WAY-855)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327877((1R*,2R*,3S*,4R*,6R*)-2-Amino-6-phenethyl-bicyclo[...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50004899((1R,2S)-2-((S)-Amino-carboxy-methyl)-cyclopropanec...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50093753((2S,3S)-2-Amino-3-benzyloxy-succinic acid | (2S,3S...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human EAAC1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327880((1R*,2R*,3S*,4R*,6R*)-2-Amino-6-butyl-bicyclo[2.2....)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327882((1R*,2R*,3S*,4R*,6R*)-2-Amino-6-[2-(4-chloro-pheny...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327878((1S*,2S*,3R*,4S*,5S*)-2-Amino-5-phenethyl-bicyclo[...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327881((1R*,2R*,3S*,4R*,6R*)-2-Amino-6-[2-(2-hydroxy-phen...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327879((1R*,2R*,3S*,4R*,6R*)-2-Amino-6-propyl-bicyclo[2.2...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50417031(CHEMBL2062159 | WAY-855)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human EAAC1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University Of Berne

Curated by ChEMBL
LigandPNGBDBM50327876((1R*,2R*,3S*,4R*,6S*)-2-Amino-6-vinyl-bicyclo-[2.2...)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed