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Found 18 with Last Name = 'bach' and Initial = 'ma'
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50411445(CHEMBL235658)
Affinity DataKi:  330nMAssay Description:Inhibition of MK2 in human TERT immortalised HCA2 cells assessed as inhibition of anisomycin-induced HSP27 phosphorylation at 2.5 uM by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066086(1N-{6-[1'-[2-(1-amino-1-methylethylcarboxamido)-3-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory concentration of the compound (biotinylated probe) is evaluated for [35S]- MK-0677 bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066092(3N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  68nMAssay Description:Antagonistic activity against Oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxytocin receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066084(3N-[7,7-dimethyl-1-spiro[2,3-dihydro-1H-indene-1,4...)
Affinity DataIC50:  130nMAssay Description:Antagonistic activity against Oxytocin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50225787(2,4-diamino-6,7-dihydroxy-10H-9-oxa-1-aza-anthrace...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MK2 in human TERT immortalised HCA2 cells assessed as inhibition of anisomycin-induced HSP27 phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50242977(CHEMBL500862 | Cepharanthine | cepharantine)
Affinity DataIC50:  1.50E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85440(Lindoldhamine (R,R))
Affinity DataIC50:  2.70E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85441(Daphnoline (R,S))
Affinity DataIC50:  5.00E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50241641((+)-Homoaromoline | CHEMBL509855 | Homoaromoline |...)
Affinity DataIC50:  5.50E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85442(Gyrocarpine (S,R))
Affinity DataIC50:  5.80E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM50292467(Antioquine | Antioquine (S,R) | CHEMBL446564 | CHE...)
Affinity DataIC50:  6.00E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM41947((-)-BEBEERINE | MLS000069827 | SMR000058852 | bebe...)
Affinity DataIC50:  6.00E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85443(Limacine (R,R))
Affinity DataIC50:  9.00E+4nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85444(CHEMBL506025 | Isotetrandrine (R,S) | Pheanthine (...)
Affinity DataIC50:  1.22E+5nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85444(CHEMBL506025 | Isotetrandrine (R,S) | Pheanthine (...)
Affinity DataIC50:  2.35E+5nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Crithidia fasciculata)
Orstom

LigandPNGBDBM85446(Cycleanine (R,R))
Affinity DataIC50:  3.03E+5nMpH: 7.8 T: 2°CAssay Description:Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50049478(1-{[(2R)-3-(benzyloxy)-1-{1-methanesulfonyl-1,2-di...)
Affinity DataKd:  0.140nMAssay Description:Compound was evaluated for binding affinity using [35S]-MK-0677 (800-1100 Ci/mmol), as radioligand having specific high activityMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50066101(CHEMBL322912 | Piperidine-4-carboxylic acid {(R)-1...)
Affinity DataEC50:  0.340nMAssay Description:Compound was evaluated for GH release for effect on human GH secretagogue receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed