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Found 763 with Last Name = 'bae' and Initial = 'k'
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50135168(3,4,5-Trihydroxy-benzoic acid (2R,3S)-5,7-dihydrox...)
Affinity DataKi:  170nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50135163(3,4,5-Trihydroxy-benzoic acid (2S,3S)-5,7-dihydrox...)
Affinity DataKi:  210nMAssay Description:Inhibition of human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM50135164(3,4,5-Trihydroxy-benzoic acid (2S,3S)-2-(3,4-dihyd...)
Affinity DataKi:  5.30E+3nMAssay Description:Inhibitory activity of the compound against recombinant human Beta-secretase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50228403((R)-8-(3-aminopiperidin-1-yl)-7-(but-2-ynyl)-3-met...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364156(CHEMBL1951432)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364171(CHEMBL1951598)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  0.760nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347364(US10301320, ID SW206980 | US10869871, ID # SW20698...)
Affinity DataIC50:  0.970nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347365(US10301320, ID SW206992 | US10869871, ID # SW20699...)
Affinity DataIC50:  0.970nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347364(US10301320, ID SW206980 | US10869871, ID # SW20698...)
Affinity DataIC50:  0.970nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347364(US10301320, ID SW206980 | US10869871, ID # SW20698...)
Affinity DataIC50:  0.970nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364187(CHEMBL1951416)
Affinity DataIC50:  1nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364173(CHEMBL1951599)
Affinity DataIC50:  1nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364184(CHEMBL1951611)
Affinity DataIC50:  1nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364158(CHEMBL1951430)
Affinity DataIC50:  1nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347384(US10869871, ID # SW208436 | US20230285402, ID # SW...)
Affinity DataIC50:  1.14nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347384(US10869871, ID # SW208436 | US20230285402, ID # SW...)
Affinity DataIC50:  1.14nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  1.23nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347359(US10301320, ID SW033291 | US10869871, ID # SW03329...)
Affinity DataIC50:  1.23nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347429(US10869871, ID # SW209415 | US20230285402, ID # SW...)
Affinity DataIC50:  1.30nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347429(US10869871, ID # SW209415 | US20230285402, ID # SW...)
Affinity DataIC50:  1.30nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347379(US10869871, ID # SW211668-(33291-R | US20230285402...)
Affinity DataIC50:  1.34nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347379(US10869871, ID # SW211668-(33291-R | US20230285402...)
Affinity DataIC50:  1.34nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347368(US10301320, ID SW208066 | US10869871, ID # SW20806...)
Affinity DataIC50:  1.37nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347391(US10869871, ID # SW208496 | US20230285402, ID # SW...)
Affinity DataIC50:  1.37nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347368(US10301320, ID SW208066 | US10869871, ID # SW20806...)
Affinity DataIC50:  1.37nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347368(US10301320, ID SW208066 | US10869871, ID # SW20806...)
Affinity DataIC50:  1.37nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347391(US10869871, ID # SW208496 | US20230285402, ID # SW...)
Affinity DataIC50:  1.37nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347368(US10301320, ID SW208066 | US10869871, ID # SW20806...)
Affinity DataIC50:  1.37nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347365(US10301320, ID SW206992 | US10869871, ID # SW20699...)
Affinity DataIC50:  1.41nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM348758(US9790233, ID SW206992)
Affinity DataIC50:  1.41nMAssay Description:In vivo assays for 15-PGDH expression or 15-PGDH activity, e.g., ligands, agonists, antagonists, and their homologs and mimetics. The term modulator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347365(US10301320, ID SW206992 | US10869871, ID # SW20699...)
Affinity DataIC50:  1.41nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347365(US10301320, ID SW206992 | US10869871, ID # SW20699...)
Affinity DataIC50:  1.41nMAssay Description:This Example provides data on a group of structural analogues of SW033291. Data provided includes level of induction of a 15-PGDH-luciferase fusion g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347388(US10869871, ID # SW208488 | US20230285402, ID # SW...)
Affinity DataIC50:  1.43nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347388(US10869871, ID # SW208488 | US20230285402, ID # SW...)
Affinity DataIC50:  1.43nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364147(CHEMBL1951595)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347405(US10869871, ID # SW209124 | US20230285402, ID # SW...)
Affinity DataIC50:  1.83nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347405(US10869871, ID # SW209124 | US20230285402, ID # SW...)
Affinity DataIC50:  1.83nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347402(US10869871, ID # SW208781 | US20230285402, ID # SW...)
Affinity DataIC50:  1.99nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347402(US10869871, ID # SW208781 | US20230285402, ID # SW...)
Affinity DataIC50:  1.99nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364183(CHEMBL1951609)
Affinity DataIC50:  2nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364179(CHEMBL1951607)
Affinity DataIC50:  2nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364177(CHEMBL1951603)
Affinity DataIC50:  2nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364167(CHEMBL1951600)
Affinity DataIC50:  2nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50364186(CHEMBL1951614)
Affinity DataIC50:  2nMAssay Description:Inhibition of human C-terminal step-tagged DPP4 expressed using baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347386(US10869871, ID # SW208437 | US20230285402, ID # SW...)
Affinity DataIC50:  2.05nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347386(US10869871, ID # SW208437 | US20230285402, ID # SW...)
Affinity DataIC50:  2.05nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347416(US10869871, ID # SW209276 | US20230285402, ID # SW...)
Affinity DataIC50:  2.09nMAssay Description:It is not clearly defined.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347416(US10869871, ID # SW209276 | US20230285402, ID # SW...)
Affinity DataIC50:  2.09nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Homo sapiens (Human))
Case Western Reserve University

US Patent
LigandPNGBDBM347406(US10869871, ID # SW209125 | US20230285402, ID # SW...)
Affinity DataIC50:  2.13nMAssay Description:Assays were done by measuring the transfer of tritium from 15(S)-[15-3H] PGE2 to glutamate (at 1 μM PGE2 substrate), or by direct fluorescence m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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