Compile Data Set for Download or QSAR
maximum 50k data
Found 180 with Last Name = 'baribaud' and Initial = 'f'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339029(5-({4-[(3S)-4-(5-Bromo-2,3-dihydro-1H-inden-1-yl)-...)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at CCR5 in IL-10 stimulated human PBMC cells assessed as MIP-1beta induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339030(4,6-Dimethyl-5-[(4-methyl-4-{(3S)-3-methyl-4-[5-(t...)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at CCR5 in IL-10 stimulated human PBMC cells assessed as MIP-1beta induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50145685((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(R)-2-met...)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at CCR5 in IL-10 stimulated human PBMC cells assessed as MIP-1beta induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50:  1.5nMAssay Description:Antagonist activity at CCR5 assessed as inhibition of receptor internalizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337608(CHEMBL1683063 | cis-((1S,3R)-3-(3-ethyl-tetrahydro...)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337604(CHEMBL1683059 | Cis-((1S,3R)-1-isopropyl-3-(3-meth...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Mus musculus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  2.80nMAssay Description:Binding affinity to mouse CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Rattus norvegicus)
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  2.90nMAssay Description:Binding affinity to rat CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50145685((4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(R)-2-met...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 in IL-10-stimulated human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at CCR5 in IL-10 stimulated human PBMC cells assessed as MIP-1beta induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at CCR5 assessed as inhibition of ERK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337604(CHEMBL1683059 | Cis-((1S,3R)-1-isopropyl-3-(3-meth...)
Affinity DataIC50:  3.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1-induced chemotaxis by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339032(5-[(4-(3S)-4-[(1R,2R)-2-methoxy-5-(trifluoromethyl...)
Affinity DataIC50:  3.5nMAssay Description:Antagonist activity at CCR5 in IL-10 stimulated human PBMC cells assessed as MIP-1beta induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  3.90nMAssay Description:Antagonist activity at human CCR2 by whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339029(5-({4-[(3S)-4-(5-Bromo-2,3-dihydro-1H-inden-1-yl)-...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 in IL-10-stimulated human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339029(5-({4-[(3S)-4-(5-Bromo-2,3-dihydro-1H-inden-1-yl)-...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 in IL-10-stimulated human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  4.30nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50346294(CHEMBL1782377 | cis-((1S,3R)-1-isopropyl-3-(((3S,4...)
Affinity DataIC50:  4.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339032(5-[(4-(3S)-4-[(1R,2R)-2-methoxy-5-(trifluoromethyl...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 in IL-10-stimulated human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337608(CHEMBL1683063 | cis-((1S,3R)-3-(3-ethyl-tetrahydro...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339030(4,6-Dimethyl-5-[(4-methyl-4-{(3S)-3-methyl-4-[5-(t...)
Affinity DataIC50:  5nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 in IL-10-stimulated human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337619(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxytetrahydr...)
Affinity DataIC50:  5.30nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)
Affinity DataIC50:  5.70nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337605(CHEMBL1683060 | Cis-((1S,3R)-1-isopropyl-3-(3-meth...)
Affinity DataIC50:  5.70nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337618(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  6.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337618(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  6.20nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50346294(CHEMBL1782377 | cis-((1S,3R)-1-isopropyl-3-(((3S,4...)
Affinity DataIC50:  6.40nMAssay Description:Antagonist activity at human CCR2 by whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50339033(5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)...)
Affinity DataIC50:  6.5nMAssay Description:Displacement of [125I]MIP-1beta from CCR5 in IL-10-stimulated human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)
Affinity DataIC50:  6.90nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337612(CHEMBL1683067 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)
Affinity DataIC50:  7nMAssay Description:Displacement of MCP-Alexa 488 from CCR2 in human whole blood after 5 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50346310(CHEMBL1782376 | cis-((1S,3R)-3-(3-oxabicyclo[3.3.1...)
Affinity DataIC50:  7.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50346304(CHEMBL1782572 | cis-(((1S,3R)-1-isopropyl-3-((3S,4...)
Affinity DataIC50:  7.70nMAssay Description:Antagonist activity at human CCR2 assessed as inhibition of MCP1-induced chemotaxis by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50346304(CHEMBL1782572 | cis-(((1S,3R)-1-isopropyl-3-((3S,4...)
Affinity DataIC50:  8.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  8.40nMAssay Description:Displacement of labeled MIP-1beta from human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  8.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50346311(CHEMBL1782573 | cis-((1S,3R)-1-isopropyl-3-((3S,4S...)
Affinity DataIC50:  8.80nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  8.90nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50346308(CHEMBL1782578 | cis-((1S,3R)-3-((4S)-3-ethyltetrah...)
Affinity DataIC50:  9.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337622(((1S,3R)-1-ethyl-3-((3S,4S)-3-methoxy-tetrahydro-2...)
Affinity DataIC50:  9.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50346295(CHEMBL1782375 | cis-((1S,3R)-3-(hexahydropyrano[4,...)
Affinity DataIC50:  9.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 preincubated for 30 mins by human whole cell binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50337620(((1S,3R)-1-isopropyl-3-((3S,4S)-3-methoxy-tetrahyd...)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]MCP1 from human CCR2 after 30 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50337634(((1S,3R)-3-((3S,4S)-3-methoxy-tetrahydro-2H-pyran-...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human CCR5 receptor by chemotaxis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 180 total ) | Next | Last >>
Jump to: