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Found 27 with Last Name = 'bartunek' and Initial = 'p'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataIC50:  0.508nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM19214((1S,2R,10S,11S,14S,15R,17S)-17-hydroxy-14-(2-hydro...)
Affinity DataIC50:  9.27nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  10.7nMAssay Description:Antagonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity after 18 hrs by lu...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  21.0nMAssay Description:Antagonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity after 18 hrs by l...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataIC50:  3.13E+3nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataIC50:  3.81E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417030(CHEMBL1257167)
Affinity DataIC50:  5.14E+3nMAssay Description:Antagonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417022(CHEMBL1258783)
Affinity DataIC50:  1.36E+4nMAssay Description:Antagonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as inhibition of transactivation activity a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417026(CHEMBL1256105)
Affinity DataEC50:  6.73nMAssay Description:Agonist activity at glucocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataEC50:  129nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417027(CHEMBL1256103)
Affinity DataEC50:  52nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417028(CHEMBL1258902)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417029(CHEMBL1257168)
Affinity DataEC50:  5.19E+3nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417023(CHEMBL1258901)
Affinity DataEC50:  35.5nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417030(CHEMBL1257167)
Affinity DataEC50:  403nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417028(CHEMBL1258902)
Affinity DataEC50:  485nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50318293(17alpha-[2-Cyano-2-(ethoxycarbonyl)-1,3-dihydro-2H...)
Affinity DataEC50:  6.92nMAssay Description:Transactivation of human ERalpha expressed in HEK293 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  0.458nMAssay Description:Agonist activity at ERbeta-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucifer...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataEC50:  2.77nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417022(CHEMBL1258783)
Affinity DataEC50:  9.95E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417027(CHEMBL1256103)
Affinity DataEC50:  1.03E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417029(CHEMBL1257168)
Affinity DataEC50:  4.03E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50318293(17alpha-[2-Cyano-2-(ethoxycarbonyl)-1,3-dihydro-2H...)
Affinity DataEC50:  22.7nMAssay Description:Transactivation of human ERbeta expressed in HEK293 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50318292(17alpha-[2,2-Bis(ethoxycarbonyl)-1,3-dihydro-2H-in...)
Affinity DataEC50:  174nMAssay Description:Transactivation of human ERbeta expressed in HEK293 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417024(CHEMBL1256102)
Affinity DataEC50:  2.08E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM19214((1S,2R,10S,11S,14S,15R,17S)-17-hydroxy-14-(2-hydro...)
Affinity DataEC50:  0.338nMAssay Description:Agonist activity at mineralocorticoid receptor-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity aft...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Charles University In Prague

Curated by ChEMBL
LigandPNGBDBM50417025(CHEMBL1257284)
Affinity DataEC50:  1.66E+3nMAssay Description:Agonist activity at ERalpha-LBD in human U2OS cells transfected with Gal4-DBD assessed as increase of transactivation activity after 18 hrs by lucife...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed