Compile Data Set for Download or QSAR
maximum 50k data
Found 814 with Last Name = 'bilsky' and Initial = 'e'
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.0620nMAssay Description:Apparent antagonist activity determined by measuring the ability to inhibit stimulation of [35S]GTP-gamma-S, binding to opioid receptor delta 1 in gu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50545673(CHEMBL4634079)
Affinity DataKi: <0.169nMAssay Description:Displacement of [3H]-diprenorphine from human delta opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50080467(5'-(Chlorophenyl)-17-(cyclopropylmethyl) -6,7-dide...)
Affinity DataKi:  0.180nMAssay Description:Apparent antagonist activity determined by measuring the ability to inhibit stimulation of [35S]GTP-gamma-S, binding to opioid receptor delta 1 in gu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50217952((1R,5R,9S)-(-)-9-hydroxy-5-(3-hydroxyphenyl-2-phen...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50217956((1R,5S)-(+)-5-(3-hydroxyphenyl)-9-methylene-2-phen...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50108973(CHEMBL3597078)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50108977(CHEMBL3597154)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in African green monkey COS1 cell membranes after 1.5 hrs by scintillation counting ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.410nMAssay Description:Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50398759(CHEMBL2179655)
Affinity DataKi:  0.410nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342116((S)-(1,3,4-oxadiazol-2-yl)(6-phenoxy-1,2,3,4-tetra...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50545677(CHEMBL4645508)
Affinity DataKi: <0.510nMAssay Description:Displacement of [3H]-diprenorphine from human kappa opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50398758(CHEMBL2179656)
Affinity DataKi:  0.540nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50297503(17-(cyclopropylmethyl)-3,14-dihydroxy-6beta-(N,N-d...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.560nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50217950((1R,5S,9R)-(+)-5-(3-hydroxyphenyl)-9-methyl-2-phen...)
Affinity DataKi:  0.600nMAssay Description:Displacement of [125I]IOXY from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50217956((1R,5S)-(+)-5-(3-hydroxyphenyl)-9-methylene-2-phen...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [125I]IOXY from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50398760(CHEMBL2179652)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity at opioid receptor delta 1 by displacement of [3H]DADLE in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50297505(CHEMBL563988 | l7-(cyclopropylmethyl)-3,l4-dihydro...)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50080459(17-(Cyclopropyl-methyl) -6, 7-didehydro-3,14-dihyd...)
Affinity DataKi:  0.870nMAssay Description:Binding affinity at opioid receptor delta 1 by displacement of [3H]DADLE in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50001196(CHEMBL610522)
Affinity DataKi:  0.870nMAssay Description:Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50398750(CHEMBL2179662)
Affinity DataKi:  0.940nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398750(CHEMBL2179662)
Affinity DataKi:  0.960nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398751(CHEMBL2179661)
Affinity DataKi:  0.970nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50398753(CHEMBL2179658)
Affinity DataKi:  1nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342118((S)-(6-phenoxy-1,2,3,4-tetrahydronaphthalen-2-yl)(...)
Affinity DataKi:  1nMAssay Description:Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398758(CHEMBL2179656)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398759(CHEMBL2179655)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50297506(CHEMBL551074 | l7-(cyclopropylmethyl)-3,l4-dihydro...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50140900(6-(2,4-dichlorophenyl)-19-methyl-(2R,10R)-11-oxa-8...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity at opioid receptor delta 1 by displacement of [3H]DADLE in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50140900(6-(2,4-dichlorophenyl)-19-methyl-(2R,10R)-11-oxa-8...)
Affinity DataKi:  1.10nMAssay Description:Apparent antagonist activity determined by measuring the ability to inhibit stimulation of [35S]GTP-gamma-S, binding to opioid receptor delta 1 in gu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50545677(CHEMBL4645508)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-diprenorphine from human mu opioid receptor expressed in CHO cell membranes incubated for 1 hr by competition radioligand bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398760(CHEMBL2179652)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398753(CHEMBL2179658)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342064((S)-2-(6-phenoxy-1,2,3,4-tetrahydronaphthalene-2-c...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50398751(CHEMBL2179661)
Affinity DataKi:  1.40nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342123((R)-(1,3,4-oxadiazol-2-yl)(6-phenoxy-1,2,3,4-tetra...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342104((S)-(5-(benzyloxy)-2,3-dihydro-1H-inden-2-yl)(5-(p...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Institute On Drug Abuse

Curated by ChEMBL
LigandPNGBDBM50108960(CHEMBL3597153)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50398758(CHEMBL2179656)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity at Opioid receptor mu 1 by displacement of [3H]DAMGO in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50123273(19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342117((S)-methyl 5-(6-phenoxy-1,2,3,4-tetrahydronaphthal...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50398759(CHEMBL2179655)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity at opioid receptor delta 1 by displacement of [3H]DADLE in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398755(CHEMBL2179653)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342124((R)-methyl 5-(6-phenoxy-1,2,3,4-tetrahydronaphthal...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of full-length human FAAH expressed in COS-7 cells assessed as [14C]-labeled oleamide to oleic acid conversionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50140913(6-(4-chlorophenyl)-19-cyclopropylmethyl-(2R,10R)-1...)
Affinity DataKi:  1.60nMAssay Description:Apparent antagonist activity determined by measuring the ability to inhibit stimulation of [35S]GTP-gamma-S, binding to opioid receptor delta 1 in gu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Alabama At Birmingham

Curated by ChEMBL
LigandPNGBDBM50297505(CHEMBL563988 | l7-(cyclopropylmethyl)-3,l4-dihydro...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 814 total ) | Next | Last >>
Jump to: