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Found 22 with Last Name = 'caaveiro' and Initial = 'jm'
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataKi:  56nMAssay Description:Irreversible inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substr...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591390(CHEMBL5190754)
Affinity DataKi:  224nMAssay Description:Irreversible inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM496902(CVD-0018409 | PF-07321332 | US11351149, Example 13...)
Affinity DataIC50:  0.790nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM420298(CVD-0006356 | PF-00835231 | PF-0835231 | US1152494...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPurchasePDB
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591391(CHEMBL5179611)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591388(CHEMBL5198073)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591392(CHEMBL5195394)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591390(CHEMBL5190754)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591394(CHEMBL5172924)
Affinity DataIC50:  332nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591393(CHEMBL5197241)
Affinity DataIC50:  464nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 3CLpro expressed in Escherichia coli using Ac-Abu-Tle-Leu-Gln-MCA as fluorogenic substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of C-terminal His-tagged recombinant Human cathepsin L (18 to 333 residues) expressed in FreeStyle 293-F cells using Z-Leu-Arg-MCA peptide...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin S(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of C-terminal His-tagged recombinant Human cathepsin S (17 to 331 residues) expressed in FreeStyle 293-F cells using Z-Leu-Arg-MCA peptide...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCathepsin B(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50591389(CHEMBL5179778)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of C-terminal His-tagged Human cathepsin B expressed in FreeStyle 293-F cells using Z-Leu-Arg-MCA peptide as fluorogenic substrate preincu...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteroid Delta-isomerase(Pseudomonas putida)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50292538((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataKd:  1.80E+5nMAssay Description:Binding affinity to Pseudomonas putida KSI by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid Delta-isomerase(Pseudomonas putida)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50427552(CHEMBL382602)
Affinity DataKd:  6.30E+4nMAssay Description:Binding affinity to Pseudomonas putida KSI by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid Delta-isomerase(Pseudomonas putida)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50427551(CHEMBL1499599)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to Pseudomonas putida KSI by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid Delta-isomerase(Pseudomonas putida)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50375599(DEOXYCHOLATE | Deoxycholic Acid | KYBELLA)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to Pseudomonas putida KSI by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50229978(5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOL...)
Affinity DataKd:  850nMAssay Description:Binding affinity to ERK2 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetSteroid Delta-isomerase(Pseudomonas putida)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50427553(CHEMBL1338939)
Affinity DataKd:  4.60E+4nMAssay Description:Binding affinity to Pseudomonas putida KSI by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid Delta-isomerase(Pseudomonas putida)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50427554(3-(3-(Trifluoromethyl)Phenyl)Acrylamide | CHEMBL10...)
Affinity DataKd:  5.00E+4nMAssay Description:Binding affinity to Pseudomonas putida KSI by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid Delta-isomerase(Pseudomonas putida)
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50375599(DEOXYCHOLATE | Deoxycholic Acid | KYBELLA)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to Pseudomonas putida KSI by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank