Affinity DataKi: 0.0400nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:In vitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.120nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Competitive binding versus [N-methyl-3H]-WIN 35,428 in murine kidney cells transfected with human dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H](R,S)citalopram.HBr from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:In vitro affinity determined using [3H]-WIN- 35428 in murine kidney cells transfected with human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:In vitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 0.490nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:In vitro affinity determined using [3H]-citalopram in murine kidney cells transfected with human serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.670nMAssay Description:In vitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Inhibition constant against [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with human dopamine transporter.More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:In vitro binding affinity of the compound was determined against human norepinephrin transporter in human embryonic kidney cell line by using [3H]-ni...More data for this Ligand-Target Pair
Affinity DataKi: 1.15nMAssay Description:Invitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
Affinity DataKi: 1.35nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Invitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:In vitro competitive binding versus [3H]- nisoxatine in murine kidney cells transfected with cDNA for human norepinephrine transporter (NET)More data for this Ligand-Target Pair
Affinity DataKi: 1.46nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.78nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.86nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.88nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 1.98nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.25nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.26nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:In vitro binding affinity of the compound was determined against human norepinephrin transporter in human embryonic kidney cell line by using [125I]-...More data for this Ligand-Target Pair
Affinity DataKi: 3.08nMAssay Description:Inhibition constant against [3H]-citalopram in murine kidney cells transfected with human dopamine transporterMore data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.45nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.47nMAssay Description:In vitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4.16nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 4.67nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 4.88nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.25nMAssay Description:In vitro binding affinity of the compound was determined against human dopamine transporter in dog kidney cell line by using [3H]-WIN- 35,428 as the ...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:In vitro binding affinity of the compound was determined against human norepinephrin transporter in human embryonic kidney cell line by using [125I]-...More data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 6.42nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair