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Found 35 with Last Name = 'cardoso' and Initial = 'mv'
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50117291(CHEMBL3613587)
Affinity DataIC50:  8nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058809(CHEMBL3329524)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50114613((1E)-1-(3-bromophenyl)propan-1-one thiosemicarbazo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50114613((1E)-1-(3-bromophenyl)propan-1-one thiosemicarbazo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058806(CHEMBL3329519)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50114653((1E)-1-(3,4-dichlorophenyl)ethan-1-one thiosemicar...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Trypanosoma cruzi Cruzain using Z-FR-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50330929(2-[(p-Methylphenyl)thiopropylidenehydrazinyl]-5-me...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50117285(CHEMBL3613583)
Affinity DataIC50:  70nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50114653((1E)-1-(3,4-dichlorophenyl)ethan-1-one thiosemicar...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50330926(2-[(p-Chlorophenylthio)propylide-1-enehydrazinyl]-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058805(CHEMBL3329518)
Affinity DataIC50:  300nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50330928(2-[(Phenylthio)propylide-1-enehydrazinyl]-5-methyl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50117281(CHEMBL3613582)
Affinity DataIC50:  400nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058804(CHEMBL3329515)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058808(CHEMBL3329521)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558296(CHEMBL4744510)
Affinity DataIC50:  510nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50117278(CHEMBL3613569)
Affinity DataIC50:  600nMAssay Description:Inhibition of Trypanosoma cruzi catalytic activity of cruzain using Z-FR-AMC as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50282986(CHEMBL3786939)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain preincubated for 10 mins followed by Z-FR-AMC substrate addition measured for 5 mins at 12 secs t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058803(CHEMBL2409542)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058802(CHEMBL3329513)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50516805(CHEMBL3785388)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition and measured for 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558297(CHEMBL3787543)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058807(CHEMBL3329520)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50282987(CHEMBL4165151)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain preincubated for 10 mins followed by Z-FR-AMC substrate addition measured for 5 mins at 12 secs t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50058801(CHEMBL3329506)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558295(CHEMBL4782594)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558293(CHEMBL4747507)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558292(CHEMBL3787688)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558294(CHEMBL4746565)
Affinity DataIC50:  1.51E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558290(CHEMBL4744489)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50516806(CHEMBL3787052)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition and measured for 5 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558289(CHEMBL3785603)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50330927(2-[(p-Methylphenylthio)ethylidenehydrazinyl]-5-met...)
Affinity DataIC50:  2.04E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine pre-incubated for 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558291(CHEMBL4743580)
Affinity DataIC50:  3.27E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
Universidade Federal De Pernambuco

Curated by ChEMBL
LigandPNGBDBM50558288(CHEMBL3785430)
Affinity DataIC50:  4.46E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate and measured at 12 sec interval for 5 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed