TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >0.000100nMAssay Description:Compound was evaluated for its binding affinity towards human Endothelin A receptorMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >0.000100nMAssay Description:Compound was evaluated for its binding affinity towards rat Angiotensin II receptor, type 1More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >0.000100nMAssay Description:Compound was evaluated for its binding affinity towards human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 0.0480nMAssay Description:Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.130nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.150nMAssay Description:Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Displacement of [3H]E2 from rat ERbeta1 after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Inhibition constant was evaluated against Histamine N-methyl-transferaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]estradiol from human full-length ERbeta receptor by competitive radiometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Displacement of [3H]estradiol from human full-length ERbeta receptor by competitive radiometric binding assayMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity towards Angiotensin II receptor, type 1 in rat aortic smooth muscle cells using 0.2 nM [125I]-labeled Sar-Ile-angiotensin IIMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]BMS-725519 from human CB1 receptor expressed in CHO cells after 90 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Compound was evaluated for its binding affinity towards rat Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity towards human ETA receptor expressed in CHO-K1 cells in the presence of 0.05 nM [125I]-labeled endothelin 1More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Compound was evaluated for its binding affinity towards human Angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Relative binding affinity for human estrogen receptor alpha compared to [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/B(RAT)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Binding affinity towards Angiotensin II receptor, type 1 in rat aortic smooth muscle cells using 0.2 nM [125I]-labeled Sar-Ile-angiotensin IIMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Compound was evaluated for its binding affinity towards human Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity to human CB1 receptor expressed in CHO cells by radioligand displacement based scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.82nMAssay Description:Displacement of [3H]E2 from rat ERbeta1 after 90 minsMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Compound was evaluated for its binding affinity towards human Endothelin A receptorMore data for this Ligand-Target Pair