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Found 165 with Last Name = 'caroli' and Initial = 'a'
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM21392(3-(2-aminoethyl)-1H-indole-5-carboxamide | 5-CT | ...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50253281(CHEMBL522691 | N-(4-Cyanophenylmethyl)-4-(2-diphen...)
Affinity DataKi:  0.580nMAssay Description:Binding affinity to rat cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395193(CHEMBL2164330)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395191(CHEMBL494675)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395187(CHEMBL2164334)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395192(CHEMBL2164336)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395189(CHEMBL2164332)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395198(CHEMBL2164329)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395203(CHEMBL2164338)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395194(CHEMBL2164343)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395199(CHEMBL2164328)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395196(CHEMBL2164339)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395195(CHEMBL2164341)
Affinity DataKi:  14.9nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50253281(CHEMBL522691 | N-(4-Cyanophenylmethyl)-4-(2-diphen...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395193(CHEMBL2164330)
Affinity DataKi:  17.4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395200(CHEMBL2164344)
Affinity DataKi:  18.4nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395202(CHEMBL2164340)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395190(CHEMBL2164331)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395196(CHEMBL2164339)
Affinity DataKi:  31.4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395188(CHEMBL2164333)
Affinity DataKi:  63.2nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395190(CHEMBL2164331)
Affinity DataKi:  72.1nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395195(CHEMBL2164341)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007407(1-NP | 1-Naphthalen-1-yl-piperazine | 4-Naphthalen...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395205(CHEMBL2164335)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395201(CHEMBL2164342)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395191(CHEMBL494675)
Affinity DataKi:  99nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395188(CHEMBL2164333)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395194(CHEMBL2164343)
Affinity DataKi:  149nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50001862((N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl...)
Affinity DataKi:  243nMAssay Description:Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50001915(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)
Affinity DataKi:  352nMAssay Description:Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395192(CHEMBL2164336)
Affinity DataKi:  476nMAssay Description:Displacement of [3H]-8-OH-DPAT from human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395204(CHEMBL2164337)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]-5-CT from human cloned 5HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of maize histone deacetylase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  30nMAssay Description:Inhibition of maize histone deacetylase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM8611(4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonit...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50263871(1-[2-Biphenyl-4-yl-1-(4-fluoro-benzyl)-ethyl]-1H-i...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50166156((E)-N-Hydroxy-3-{4-[3-(2-methoxy-phenyl)-3-oxo-pro...)
Affinity DataIC50:  170nMAssay Description:Inhibition of maize histone deacetylase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRmtA(Emericella nidulans)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50206441(2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxo-6H-xanthen-9...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Aspergillus nidulans recombinant GST-RmtA expressed in BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50166159((E)-3-{4-[3-(2-Bromo-phenyl)-3-oxo-propenyl]-1-met...)
Affinity DataIC50:  180nMAssay Description:Inhibition of maize histone deacetylase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50263761(Biphenyl-4-ylmethyl-(4-fluoro-benzyl)-imidazol-1-y...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50134804((E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-phenyl-pr...)
Affinity DataIC50:  260nMAssay Description:Inhibition of maize histone deacetylase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50263924(1-[2-Biphenyl-4-yl-1-(2,4-difluoro-benzyl)-ethyl]-...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50263719(Biphenyl-4-ylmethyl-(2-chloro-benzyl)-imidazol-1-y...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50263461(CHEMBL517347 | N-(5-chlorothiophen-2-ylmethyl)-N-(...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50166158((E)-N-Hydroxy-3-[1-methyl-4-(3-naphthalen-1-yl-3-o...)
Affinity DataIC50:  330nMAssay Description:Inhibition of maize histone deacetylase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50263808(Biphenyl-4-ylmethyl-(2,4-difluoro-benzyl)-imidazol...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50134800((E)-N-Hydroxy-3-[1-methyl-4-((E)-3-oxo-3-o-tolyl-p...)
Affinity DataIC50:  390nMAssay Description:Inhibition of maize histone deacetylase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50395192(CHEMBL2164336)
Affinity DataIC50:  438nMAssay Description:Antagonist activity at human 5HT7A receptor expressed in human HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50263720(Biphenyl-4-ylmethyl-(2-fluoro-benzyl)-imidazol-1-y...)
Affinity DataIC50:  460nMAssay Description:Inhibition of human aromataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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