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Found 128 with Last Name = 'carroll' and Initial = 'ar'
TargetCoagulation factor VII(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269766(CHEMBL455257 | dysinosin B)
Affinity DataKi:  90nMAssay Description:Inhibition of factor 7a (unknown origin) by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269776(CHEMBL502639 | Dysinosin A)
Affinity DataKi:  108nMAssay Description:Inhibition of factor 7a (unknown origin) by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269767(CHEMBL508298 | dysinosin C)
Affinity DataKi:  124nMAssay Description:Inhibition of factor 7a (unknown origin) by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269766(CHEMBL455257 | dysinosin B)
Affinity DataKi:  170nMAssay Description:Inhibition of thrombin (unknown origin) by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269776(CHEMBL502639 | Dysinosin A)
Affinity DataKi:  452nMAssay Description:Inhibition of thrombin (unknown origin) by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269767(CHEMBL508298 | dysinosin C)
Affinity DataKi:  550nMAssay Description:Inhibition of thrombin (unknown origin) by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269768(CHEMBL518066 | dysinosin D)
Affinity DataKi:  1.32E+3nMAssay Description:Inhibition of factor 7a (unknown origin) by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269768(CHEMBL518066 | dysinosin D)
Affinity DataKi: >5.10E+3nMAssay Description:Inhibition of thrombin (unknown origin) by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [3H]deltorphin-2 from human delta opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)
Affinity DataIC50:  5nMAssay Description:Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50381677(CHEMBL1256748 | U-69593)
Affinity DataIC50:  8nMAssay Description:Displacement of [3H]naloxone from kappa opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50072394(1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyr...)
Affinity DataIC50:  23nMAssay Description:Displacement of [3H]3-methylhistidyl-TRH from rat recombinant TRHR2 expressed in HEK2935 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  28nMAssay Description:Inhibition of Pim2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  138nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  138nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  138nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50000788((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...)
Affinity DataIC50:  138nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  150nMAssay Description:Inhibition of GST-tagged MAPKAPK2 assessed as [33P] incorporation after 40 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAspartate-semialdehyde dehydrogenase(Helicobacter pylori)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269414(CHEMBL457665 | CYSTEINE-S-SULFONIC ACID | S-sulpho...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Helicobacter pylori His-tagged ASD assessed as inhibition of phosphorylation of aspartate semialdehydeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50233004(2-(3-carbamimidamidopropylidene)butanedioic acid |...)
Affinity DataIC50:  360nMAssay Description:Inhibition of carboxypeptidase BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50316549(CHEMBL1097805 | longanine)
Affinity DataIC50:  700nMAssay Description:Displacement of [3H]deltorphin-2 from human delta opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50216277(4,4'-((1R,2R,3S,4S)-3,4-dimethylcyclobutane-1,2-di...)
Affinity DataIC50:  900nMAssay Description:Binding affinity to glucocorticoid receptor by GR binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50271071((2,4-Dibromo-3-{[(4-carbamimidamidobutyl)carbamoyl...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of factor 11a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269337(CHEMBL497516 | Grandisine F)
Affinity DataIC50:  1.55E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269336(grandisine D)
Affinity DataIC50:  1.65E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50225276(6-(3,3'-dihydroxy-4'-sulfooxy-biphenyl-4-yloxy)-2,...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50225828((2Z,2'Z)-N,N'-{butane-1,4-diylbis[(methylimino)pro...)
Affinity DataIC50:  1.90E+3nMAssay Description:Displacement of [3H]SAM from Icmt relative to SAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50316551(CHEMBL1096481 | N-methylstephuline)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [3H]deltorphin-2 from human delta opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50316546(CHEMBL1097077 | N-methylstephisoferulin)
Affinity DataIC50:  2.50E+3nMAssay Description:Displacement of [3H]deltorphin-2 from human delta opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50211219(elaeocarpenine)
Affinity DataIC50:  2.74E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50241599(CHEMBL453012 | sideroxylonal A)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human PAI1 using tissue type plasminogen activator substrate by plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50225277(2,8-dihydroxy-6-(3,3',4'-trihydroxy-biphenyl-4-ylo...)
Affinity DataIC50:  3.71E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50241601(CHEMBL453538 | sideroxylonal C)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human PAI1 using tissue type plasminogen activator substrate by plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50316547(6-cinnamoylhernandine | CHEMBL1097804)
Affinity DataIC50:  5.10E+3nMAssay Description:Displacement of [3H]deltorphin-2 from human delta opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen activator inhibitor 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50241600(CHEMBL509880 | sideroxylonal B)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human PAI1 using tissue type plasminogen activator substrate by plasmon resonanceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50316552(CHEMBL1096482 | prostephabyssine)
Affinity DataIC50:  5.50E+3nMAssay Description:Displacement of [3H]deltorphin-2 from human delta opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269357((-)-isoelaeocarpiline | CHEMBL521711)
Affinity DataIC50:  9.90E+3nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50316545(6-cinnamoyl-N-methylstephasunoline | CHEMBL1098354)
Affinity DataIC50:  1.13E+4nMAssay Description:Displacement of [3H]deltorphin-2 from human delta opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50228176(peripentadenine)
Affinity DataIC50:  1.14E+4nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50216279(CHEMBL388363 | di-O-methylendiandrin A)
Affinity DataIC50:  1.30E+4nMAssay Description:Binding affinity to glucocorticoid receptor by GR binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50211216(isoelaeocarpine)
Affinity DataIC50:  1.36E+4nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50479260(APLYSAMINE 6)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of Icmt using [3H]SAM as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50269339(CHEMBL509995 | Grandisine C)
Affinity DataIC50:  1.46E+4nMAssay Description:Displacement of [125I]deltorphin 2 from human recombinant delta opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50316550(CHEMBL1097185 | aknadilactam)
Affinity DataIC50:  1.70E+4nMAssay Description:Displacement of [3H]deltorphin-2 from human delta opioid receptor expressed in HEK293 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyrotropin-releasing hormone receptor(Rattus norvegicus)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50261174(CHEMBL496930 | corymbone B)
Affinity DataIC50:  1.90E+4nMAssay Description:Displacement of [3H]3-methylhistidyl-TRH from rat recombinant TRH2 receptor expressed in HEK2935 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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