Affinity DataIC50: 0.700nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
University Of Illinois At Chicago 60612
Curated by ChEMBL
University Of Illinois At Chicago 60612
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
University Of Illinois At Chicago 60612
Curated by ChEMBL
University Of Illinois At Chicago 60612
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
University Of Illinois At Chicago 60612
Curated by ChEMBL
University Of Illinois At Chicago 60612
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of CYP2D6 using dextromethorphan as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of MAP4K4 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
University Of Illinois At Chicago 60612
Curated by ChEMBL
University Of Illinois At Chicago 60612
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
University Of Illinois At Chicago 60612
Curated by ChEMBL
University Of Illinois At Chicago 60612
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of Axl (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
University Of Illinois At Chicago 60612
Curated by ChEMBL
University Of Illinois At Chicago 60612
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 100nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of CK1-delta (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of MAP4K4 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of Mer (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of MAP3K9 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 189nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 215nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of LCK (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 246nMAssay Description:Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATPMore data for this Ligand-Target Pair