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Found 9 with Last Name = 'chan' and Initial = 'sh'
TargetCarbamoyl-phosphate synthase small chain(Escherichia coli (strain K12))
Texas A&M University

LigandPNGBDBM93010(Glutamine Analogue, 2)
Affinity DataKi:  9.00E+3nMpH: 7.5Assay Description:The rate of carbamoyl phosphate synthesis was determined by use of a coupled enzyme assay with ornithine transcarbamoylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbamoyl-phosphate synthase small chain(Escherichia coli (strain K12))
Texas A&M University

LigandPNGBDBM93009(Glutamine Analogue, 1)
Affinity DataKi:  5.40E+4nMpH: 7.5Assay Description:The rate of carbamoyl phosphate synthesis was determined by use of a coupled enzyme assay with ornithine transcarbamoylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbamoyl-phosphate synthase small chain(Escherichia coli (strain K12))
Texas A&M University

LigandPNGBDBM93011(Glutamine Analogue, 3)
Affinity DataKi:  3.40E+5nMpH: 7.5Assay Description:The rate of carbamoyl phosphate synthesis was determined by use of a coupled enzyme assay with ornithine transcarbamoylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbamoyl-phosphate synthase small chain(Escherichia coli (strain K12))
Texas A&M University

LigandPNGBDBM93013(Glutamine Analogue, 5)
Affinity DataKi:  2.50E+7nMpH: 7.5Assay Description:The rate of carbamoyl phosphate synthesis was determined by use of a coupled enzyme assay with ornithine transcarbamoylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbamoyl-phosphate synthase small chain(Escherichia coli (strain K12))
Texas A&M University

LigandPNGBDBM93012(Glutamine Analogue, 4)
Affinity DataKi:  2.80E+7nMpH: 7.5Assay Description:The rate of carbamoyl phosphate synthesis was determined by use of a coupled enzyme assay with ornithine transcarbamoylase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research

LigandPNGBDBM195606(NCT-503)
Affinity DataIC50:  2.50E+3nMpH: 8.0 T: 2°CAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research

LigandPNGBDBM195605(NCT-502 | US11225469, Compound 72)
Affinity DataIC50:  3.70E+3nMpH: 8.0 T: 2°CAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research

LigandPNGBDBM58473(MLS001172437 | N-(4-methyl-2-pyridinyl)-4-[3-(trif...)
Affinity DataIC50:  1.53E+4nMpH: 8.0 T: 2°CAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Whitehead Institute For Biomedical Research

LigandPNGBDBM195607(PHGDH-inactive | US11225469, Compound 71)
Affinity DataIC50: >5.70E+4nMpH: 8.0 T: 2°CAssay Description:PHGDH assay buffer contained 50 mM TEA pH 8.0, 10 mM MgCl2, 0.05% BSA, and 0.01% Tween-20. PHGDH enzyme buffer consisted of assay buffer with 20 nM P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed