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Found 50 with Last Name = 'classen-houben' and Initial = 'd'
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329192((3beta,18beta,20beta)-3-Acetoxy-N-methyl-N-hydroxy...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329192((3beta,18beta,20beta)-3-Acetoxy-N-methyl-N-hydroxy...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329187((3alpha,18beta,20beta)-3-Methoxyamino-11-oxo-olean...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50339809((5aR,7aR,7bS,9aS,12S,13aR,15aR,15bS)-2,3,4,5,5a,6,...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50339805((3beta,18beta,20beta)-[3-(1,2,4-Oxadiazole-5(2H)-o...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329188((3beta,18beta,20beta)-3-Methoxyamino-11-oxo-olean-...)
Affinity DataIC50:  14.5nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50339811((3beta,18beta,20beta)-N-Hydroxy-N-methyl-[3-(1,2,4...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50339812(CHEMBL1689283 | N-[(3beta,18beta,20beta)-3-Hydroxy...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50339808(CHEMBL1689279 | N-[(5aR,7aR,7bS,9aS,12S,13aR,15aR,...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329188((3beta,18beta,20beta)-3-Methoxyamino-11-oxo-olean-...)
Affinity DataIC50:  42.7nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50339813(CHEMBL1689284 | N-[(3beta,18beta,20beta)-3,11-Diox...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329193((3beta,18beta,20beta)-3-Acetoxy-N-hydroxy-11-oxo-o...)
Affinity DataIC50:  61.1nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329187((3alpha,18beta,20beta)-3-Methoxyamino-11-oxo-olean...)
Affinity DataIC50:  61.9nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  90nMAssay Description:Inhibition of rat hepatic 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  90nMAssay Description:Inhibition of 11beta-HSD1 in rat liver assessed as cortisone levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50339806((3beta,18beta,20beta)-N-[-3-(Acetoxy)-11-oxo-30-no...)
Affinity DataIC50:  104nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329195((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-N,10-dihyd...)
Affinity DataIC50:  122nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50339805((3beta,18beta,20beta)-[3-(1,2,4-Oxadiazole-5(2H)-o...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50339807(CHEMBL1689277 | N-[(3beta,18beta,20beta)-3-(Acetox...)
Affinity DataIC50:  194nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  257nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  257nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329191((2S,4aS,6aS,6bR,8aR,12aS,12bR,14bR,E)-10-(methoxyi...)
Affinity DataIC50:  268nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329190((18beta,20beta)-3,11-Dioxo-olean-12-en-29-oic acid...)
Affinity DataIC50:  329nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  360nMAssay Description:Inhibition of rat renal 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  360nMAssay Description:Inhibition of rat renal 11beta-HSD2 in rat liver assessed as inhibition of cortisone productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329189((3beta,18beta,20beta)-3-(Acetylamino)-11-oxo-olean...)
Affinity DataIC50:  458nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50339811((3beta,18beta,20beta)-N-Hydroxy-N-methyl-[3-(1,2,4...)
Affinity DataIC50:  504nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329190((18beta,20beta)-3,11-Dioxo-olean-12-en-29-oic acid...)
Affinity DataIC50:  619nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329193((3beta,18beta,20beta)-3-Acetoxy-N-hydroxy-11-oxo-o...)
Affinity DataIC50:  626nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)
Affinity DataIC50:  750nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)
Affinity DataIC50:  750nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  778nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  778nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329189((3beta,18beta,20beta)-3-(Acetylamino)-11-oxo-olean...)
Affinity DataIC50:  825nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329194((3beta,18beta,20beta)-3-Hydroxy-N-methoxy-11-oxo-o...)
Affinity DataIC50:  929nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329192((3beta,18beta,20beta)-3-Acetoxy-N-methyl-N-hydroxy...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329192((3beta,18beta,20beta)-3-Acetoxy-N-methyl-N-hydroxy...)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329195((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-N,10-dihyd...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50329191((2S,4aS,6aS,6bR,8aR,12aS,12bR,14bR,E)-10-(methoxyi...)
Affinity DataIC50:  1.51E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50329194((3beta,18beta,20beta)-3-Hydroxy-N-methoxy-11-oxo-o...)
Affinity DataIC50:  2.13E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50339807(CHEMBL1689277 | N-[(3beta,18beta,20beta)-3-(Acetox...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
University Of Technology

Curated by ChEMBL
LigandPNGBDBM50339810(1-((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50339812(CHEMBL1689283 | N-[(3beta,18beta,20beta)-3-Hydroxy...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50188385((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-acetoxy...)
Affinity DataIC50:  7.14E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-3H]-cortisone to cortisol by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50339806((3beta,18beta,20beta)-N-[-3-(Acetoxy)-11-oxo-30-no...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50339813(CHEMBL1689284 | N-[(3beta,18beta,20beta)-3,11-Diox...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50339809((5aR,7aR,7bS,9aS,12S,13aR,15aR,15bS)-2,3,4,5,5a,6,...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50339810(1-((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
University Of Natural Resources And Applied Life Sciences

Curated by ChEMBL
LigandPNGBDBM50339808(CHEMBL1689279 | N-[(5aR,7aR,7bS,9aS,12S,13aR,15aR,...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [1,2-[3H]cortisone to cortisol after 10 mins by scint...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed