TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 40nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [G550E](Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 102nMAssay Description:YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 103nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 104nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 138nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [G550E](Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 417nMAssay Description:YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator [G550E](Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 496nMAssay Description:YFP-Halide Influx Assay for the CFTR-ΔF508 Mutation and Suppressor mutants (I539T or G550E)The YFP halide influx assay measures the functionalit...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 3.25E+3nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: >6.67E+3nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.93E+4nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 6.48E+4nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 8.98E+4nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.08E+4nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.35E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.64E+5nMAssay Description:Inhibition of GID4 (124 to 289) (unknown origin) expressed in Escherichia coli BL21(DE3) using PGLWKS-FITC peptide by competitive-fluorescence polari...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataKd: 1.10E+5nMAssay Description:Binding affinity to GID4 (124 to 289) (unknown origin) assessed as dissociation constant measured by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataKd: 17nMAssay Description:Binding affinity to GID4 (124 to 289) (unknown origin) assessed as dissociation constant measured by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 9.66E+3nMAssay Description:To measure the direct binding of small molecules with CFTR, the interaction between small molecules and membrane fragments derived from HEK293 cells ...More data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataKd: 20.2nMAssay Description:To measure the direct binding of small molecules with CFTR, the interaction between small molecules and membrane fragments derived from HEK293 cells ...More data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataKd: 1.90E+3nMAssay Description:Binding affinity to GID4 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
TargetGlucose-induced degradation protein 4 homolog(Homo sapiens)
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Lunenfeld-Tanenbaum Research Institute
Curated by ChEMBL
Affinity DataKd: 80nMAssay Description:Binding affinity to GID4 (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair