Found 306 with Last Name = 'dehmel' and Initial = 'f' 
Affinity DataKi: 110nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of HDAC1 in HeLa cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burk plotMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 3nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 3nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 4nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 4nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 4nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 4nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 4nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 5nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 5nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 5nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 5nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 5nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 5nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 6nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 6nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 6nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 7nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 8nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 8nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 8nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 9nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 9nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 9nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 10nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 10nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 10nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 10nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 10nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 10nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 11nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 11nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 11nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 11nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 11nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 12nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 12nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 12nMpH: 7.5Assay Description:Akt2 inhibitory activity of compounds of the present invention was quantified employing the Akt2 TR-FRET assay as described in the following paragrap...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 13nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property
US Patent
Bayer Intellectual Property
US Patent
Affinity DataIC50: 13nMpH: 7.5Assay Description:Akt1 inhibitory activity of compounds of the present invention may be quantified0 employing the Akt1 TR-FRET assay as described in the following para...More data for this Ligand-Target Pair
