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Found 15 with Last Name = 'dejaegere' and Initial = 'a'
TargetIntegrin alpha-L(Mus musculus)
Ikerchem

Curated by ChEMBL
LigandPNGBDBM50426077(CHEMBL2315999)
Affinity DataIC50:  2.76E+4nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in mouse Lim51b cells assessed as PMA-induced adhesion to ICAM-1 expressing HSE cells measured per 10'5 cells ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Ikerchem

Curated by ChEMBL
LigandPNGBDBM50426078(CHEMBL2316248)
Affinity DataKd:  7.40E+3nMAssay Description:Binding affinity to I-domain of human integrin alphaL (amino acid residues 128 to 307) plus initial methionine expressed in Escherichia coli by NMR s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50236238((3alpha,5beta)-3-hydroxycholan-24-oic acid | 3alph...)
Affinity DataKd:  330nMAssay Description:Binding affinity to N-terminal His-tagged human VDR LBD canonical site (118 to 427) by direct isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50236238((3alpha,5beta)-3-hydroxycholan-24-oic acid | 3alph...)
Affinity DataKd:  9.52E+3nMAssay Description:Binding affinity to N-terminal His-tagged human VDR LBD low-affinity site (118 to 427) by direct isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50236238((3alpha,5beta)-3-hydroxycholan-24-oic acid | 3alph...)
Affinity DataKd:  1.89E+4nMAssay Description:Binding affinity to N-terminal His-tagged human VDR LBD (118 to 427) by reverse isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50397073(CHEMBL2171448)
Affinity DataEC50:  5nMAssay Description:Transactivation of GAL4-fused VDR ligand binding domain expressed in human HeLa cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  2.5nMAssay Description:Transactivation of full length human VDR expressed in human HeLa cells assessed as increase in CYP24 transcription after 18 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50397075(CHEMBL2171446)
Affinity DataEC50:  49nMAssay Description:Transactivation of full length human VDR expressed in human HeLa cells assessed as increase in CYP24 transcription after 18 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50397074(CHEMBL2171447)
Affinity DataEC50:  2.80nMAssay Description:Transactivation of full length human VDR expressed in human HeLa cells assessed as increase in CYP24 transcription after 18 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50397076(CHEMBL2171449)
Affinity DataEC50:  2.20nMAssay Description:Transactivation of full length human VDR expressed in human HeLa cells assessed as increase in CYP24 transcription after 18 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50397077(CHEMBL2171450)
Affinity DataEC50:  0.5nMAssay Description:Transactivation of full length human VDR expressed in human HeLa cells assessed as increase in CYP24 transcription after 18 hrs by luciferase reporte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L(Homo sapiens (Human))
Ikerchem

Curated by ChEMBL
LigandPNGBDBM34168(LOVASTATIN | MLS000069585 | SMR000058779 | US91151...)
Affinity DataKd:  1.29E+4nMAssay Description:Binding affinity to I-domain of human integrin alphaL (amino acid residues 128 to 307) plus initial methionine expressed in Escherichia coli by NMR s...More data for this Ligand-Target Pair
TargetIntegrin alpha-L(Homo sapiens (Human))
Ikerchem

Curated by ChEMBL
LigandPNGBDBM50426077(CHEMBL2315999)
Affinity DataKd:  1.01E+4nMAssay Description:Binding affinity to I-domain of human integrin alphaL (amino acid residues 128 to 307) plus initial methionine expressed in Escherichia coli by NMR s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50397074(CHEMBL2171447)
Affinity DataEC50:  1.70nMAssay Description:Transactivation of GAL4-fused VDR ligand binding domain expressed in human HeLa cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Institute Of Genetics And Molecular And Cellular Biology (Igbmc)

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  1nMAssay Description:Transactivation of GAL4-fused VDR ligand binding domain expressed in human HeLa cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank