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Found 250 with Last Name = 'derosier' and Initial = 'a'
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305799(5-((3aR,6aS)-5-(2-(1-(3,3-difluorocyclobutanecarbo...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329256(4,6-dimethyl-5-((3aR,6aS)-5-(3-(1-(methylsulfonyl)...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305800(((3aR,6aS)-5-(2-(1-(4,4-difluorocyclohexanecarbony...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305801(((3aR,6aS)-5-(2-(1-(3,3-difluorocyclobutanecarbony...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318447(CHEMBL1096764 | N-((S)-3-((3aR,6aS)-5-(2,6-dimethy...)
Affinity DataIC50:  3nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50310739((S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbony...)
Affinity DataIC50:  4nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318446(CHEMBL1096765 | N-((S)-3-((3aR,6aS)-5-(2,6-dimethy...)
Affinity DataIC50:  4nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305794(((3aR,6aS)-5-(2-(1-(4,4-difluorocyclohexanecarbony...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312846(CHEMBL1087535 | N-((S)-3-((1R,3S,5S)-3-(3,5-dimeth...)
Affinity DataIC50:  5nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312848(CHEMBL1087153 | N-((S)-3-((1R,3S,5S)-3-(3,5-dimeth...)
Affinity DataIC50:  5nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50319434((R)-3-(1'-(4,6-dimethylpyrimidine-5-carbonyl)-4'-m...)
Affinity DataIC50:  6nMAssay Description:Binding affinity at CCR5 receptor by radiolabelled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312852(CHEMBL1081476 | Exo-N-((S)-3-(5-(3,5-dimethyl-4H-1...)
Affinity DataIC50:  6nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312850(CHEMBL1082191 | Endo-N-((S)-3-(5-(3,5-dimethyl-4H-...)
Affinity DataIC50:  6nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50115528((Z)-(4-((4-bromophenyl)(ethoxyimino)methyl)-4'-met...)
Affinity DataIC50:  6nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318439(CHEMBL1097815 | N-((S)-3-((3aR,6aS)-5-(4-fluoro-2,...)
Affinity DataIC50:  6nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318451(CHEMBL1096445 | N-((S)-3-((3aR,6aS)-5-(2,6-dimethy...)
Affinity DataIC50:  6nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50310731(4-butyl-3-(cyclohexylmethyl)-8-(1-(4,6-dimethylpyr...)
Affinity DataIC50:  7nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor cotransfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312845(CHEMBL1087534 | N-((S)-3-((1R,3S,5S)-3-(3,5-dimeth...)
Affinity DataIC50:  7nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318436(CHEMBL1097169 | N-((S)-3-((3aR,6aS)-5-(2,4-dimethy...)
Affinity DataIC50:  7nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318448(CHEMBL1096768 | N-((S)-3-((3aR,6aS)-5-(2,6-dimethy...)
Affinity DataIC50:  7nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50319451((R)-3-(1'-(4,6-dimethylpyrimidine-5-carbonyl)-4'-m...)
Affinity DataIC50:  8nMAssay Description:Binding affinity at CCR5 receptor by radiolabelled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329255(4,6-dimethyl-5-((3aR,6aS)-5-(3-(1-(methylsulfonyl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312843(CHEMBL1082202 | Endo-N-((S)-3-(5-(3,5-dimethyl-4H-...)
Affinity DataIC50:  8nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318445(CHEMBL1096766 | N-((S)-3-((3aR,6aS)-5-(2,6-dimethy...)
Affinity DataIC50:  8nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318427(2-(3,3-difluorocyclobutyl)-N-((S)-3-((3aR,6aS)-5-(...)
Affinity DataIC50:  9nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318441(CHEMBL1096102 | N-((S)-3-((3aR,6aS)-5-(2-chloro-6-...)
Affinity DataIC50:  9nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305791(((3aR,6aS)-5-(2-(1-(4,4-difluorocyclohexanecarbony...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50310730(4-butyl-3-(cyclohexylmethyl)-8-(1-(2,6-dimethylben...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor cotransfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50310747((5S)-5-butyl-9-(1-(2,4-dimethylnicotinoyl)-4-methy...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor cotransfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50254720((4-(7-butyl-9-(morpholinosulfonyl)-3,9-diazaspiro[...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at CCR5 receptor (unknown origin) by radiolabelled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50329231(((3aR,6aS)-5-(3-(1-(2,2-difluoroethyl)piperidin-4-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of CCR5 by cell-cell fusion inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318449(CHEMBL1096447 | N-((S)-3-((3aR,6aS)-5-(2,6-dimethy...)
Affinity DataIC50:  11nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50310744((S)-5-butyl-9-(1-(4,6-dimethyl-2-oxo-2H-pyran-5-ca...)
Affinity DataIC50:  12nMAssay Description:Displacement of [125I]RANTES from human CCR5 receptor cotransfected with Galphai6 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50319442((R)-4,6-dimethyl-5-(4'-methyl-4-(2-oxo-5-(pyridin-...)
Affinity DataIC50:  12nMAssay Description:Binding affinity at CCR5 receptor by radiolabelled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50319447((R)-4,6-dimethyl-5-(4'-methyl-4-(2-oxo-5-phenyl-3-...)
Affinity DataIC50:  12nMAssay Description:Binding affinity at CCR5 receptor by radiolabelled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318428(2-(4,4-difluorocyclohexyl)-N-((S)-3-((3aR,6aS)-5-(...)
Affinity DataIC50:  12nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318432(CHEMBL1095827 | N-((S)-3-((3aR,6aS)-5-(6-cyano-2,4...)
Affinity DataIC50:  12nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50312847(CHEMBL1087028 | N-((S)-3-((1R,3S,5S)-3-(3,5-dimeth...)
Affinity DataIC50:  13nMAssay Description:Displacement of [128I]RANTES from human CCR5 receptor coexpressed with Galphai6 in CHO cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318429(2-cyclopentyl-N-((S)-3-((3aR,6aS)-5-(4,6-dimethylp...)
Affinity DataIC50:  13nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313879((5S)-5-butyl-9-((3aR,6aS)-2-(4,6-dimethylpyrimidin...)
Affinity DataIC50:  14nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50:  14nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318434(CHEMBL1095517 | N-((S)-3-((3aR,6aS)-5-(4,6-dimethy...)
Affinity DataIC50:  14nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318440(CHEMBL1097515 | N-((S)-3-((3aR,6aS)-5-(2,6-dichlor...)
Affinity DataIC50:  14nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305780(5-((3aR,6aS)-5-(2-(4-(3-fluorophenyl)-1-pivaloylpi...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305796(((3aR,6aS)-5-(2-(1-(4,4-difluorocyclohexanecarbony...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human recombinant CCR5 by cell-cell fusion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50313880(5-((3aR,6aS)-5-((S)-5-butyl-2-oxo-3-((tetrahydro-2...)
Affinity DataIC50:  15nMAssay Description:Displacement of [128I]-RANTES from CCR5 receptor receptors expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318443(CHEMBL1098151 | N-((S)-3-((3aR,6aS)-5-(2,6-dimethy...)
Affinity DataIC50:  15nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50318450(CHEMBL1096446 | N-((S)-3-((3aR,6aS)-5-(2,6-dimethy...)
Affinity DataIC50:  15nMAssay Description:Binding affinity at CCR5 receptor by radiolabeled RANTES binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50305798(5-((3aR,6aS)-5-(2-(1-(4,4-difluorocyclohexanecarbo...)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at human CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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