TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Competitive inhibition of human ATX using LPC (16:0) as substrate after 30 mins by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis
Curated by ChEMBL
Mutabilis
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of glycosylated human ATX using LPC 16:0 as substrate after 30 mins by luminescence assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis
Curated by ChEMBL
Mutabilis
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis
Curated by ChEMBL
Mutabilis
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis
Curated by ChEMBL
Mutabilis
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in LPA 18:2 production after 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of ATX in rat plasma assessed as reduction in plasma lysophosphatidic acid 18:2 levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human ATX using LPC (16:0) as substrate after 30 mins by horseradish peroxidase/choline oxidase coupled enzyme based spectrophotometric...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of human ATX using LPC (16:0) as substrate after 30 mins by horseradish peroxidase/choline oxidase coupled enzyme based spectrophotometric...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of glycosylated human ATX using FS-3 as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by fluore...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis
Curated by ChEMBL
Mutabilis
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis
Curated by ChEMBL
Mutabilis
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis
Curated by ChEMBL
Mutabilis
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Abbvie S.á.R.L.
US Patent
Abbvie S.á.R.L.
US Patent
Affinity DataIC50: 40nMAssay Description:For this purpose, HEK293 cells are transfected with plasmid DNA containing WT CFTR and seeded in 96 well plates (70,000 HEK cells/well). Two days aft...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis
Curated by ChEMBL
Mutabilis
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE V: 5 μL of a dilution series of compound, starting from 20 μM highest concentration, 1/5 dilution, is added to the wells. hENPP2 is u...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE V: 5 μL of a dilution series of compound, starting from 20 μM highest concentration, 1/5 dilution, is added to the wells. hENPP2 is u...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE V: 5 μL of a dilution series of compound, starting from 20 μM highest concentration, 1/5 dilution, is added to the wells. hENPP2 is u...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE V: 5 μL of a dilution series of compound, starting from 20 μM highest concentration, 1/5 dilution, is added to the wells. hENPP2 is u...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Galapagos
Curated by ChEMBL
Galapagos
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:TABLE VI: (UniProtKB/SwissProt Sequence ref Q13822) biochemical assay using the fluorogenic autotaxin substrate FS-3 as substrate. FS-3 is a doubly l...More data for this Ligand-Target Pair