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Found 2866 with Last Name = 'di cesare mannelli' and Initial = 'l'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50505384(CHEMBL4457393)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50513286(CHEMBL4470319)
Affinity DataKi:  0.200nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50341392(CHEMBL4171524)
Affinity DataKi:  0.240nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50341395(CHEMBL4175369)
Affinity DataKi:  0.25nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50341389(CHEMBL4164747)
Affinity DataKi:  0.270nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50341393(CHEMBL4165154)
Affinity DataKi:  0.280nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50511588(CHEMBL4453207)
Affinity DataKi:  0.300nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50341388(CHEMBL4159208)
Affinity DataKi:  0.310nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50341394(CHEMBL4171921)
Affinity DataKi:  0.380nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50515558(CHEMBL4535036)
Affinity DataKi:  0.420nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50515303(CHEMBL4435346)
Affinity DataKi:  0.440nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50230195(CHEMBL4100903)
Affinity DataKi:  0.440nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Sintesi e Studio di Eterocicli Biologicamente attivi (HeteroBioLab) Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50432382(CHEMBL2348441)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]Ro15-1788 from recombinant GABA-A alpha1beta2gamma2 receptor benzodiazepine binding site (unknown origin) after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50408526(CHEMBL4163381)
Affinity DataKi:  0.540nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50511587(CHEMBL4532721)
Affinity DataKi:  0.540nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Department Of University Of Florence

Curated by ChEMBL
LigandPNGBDBM50469139(CHEMBL4292479)
Affinity DataKi:  0.550nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50515559(CHEMBL4435078)
Affinity DataKi:  0.560nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50505386(CHEMBL4442908)
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cell membranes by radioligand competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50515564(CHEMBL4535469)
Affinity DataKi:  0.620nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50515563(CHEMBL4436769)
Affinity DataKi:  0.640nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50511590(CHEMBL4587627)
Affinity DataKi:  0.670nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50513291(CHEMBL4448793)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50513283(CHEMBL4534829)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50513289(CHEMBL4435918)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50513285(CHEMBL4553772)
Affinity DataKi:  0.710nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50066126(CHEMBL3402966)
Affinity DataKi:  0.720nMAssay Description:Inhibition of human recombinant CA-12 after 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50515563(CHEMBL4436769)
Affinity DataKi:  0.720nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50230205(CHEMBL4088636)
Affinity DataKi:  0.730nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50066128(CHEMBL3402964)
Affinity DataKi:  0.75nMAssay Description:Inhibition of human recombinant CA-12 after 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50511590(CHEMBL4587627)
Affinity DataKi:  0.760nMAssay Description:Inhibition of recombinant human CA7 preincubated for 15 mins by measured for 10 to 100 secs by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50341391(CHEMBL4163634)
Affinity DataKi:  0.770nMAssay Description:Inhibition of human carbonic anhydrase 7 after 15 mins by stopped flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50528166(CHEMBL4519039)
Affinity DataKi:  0.780nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated with enzyme for 1 hr prior to testing by phenol red-based stopped-flow CO2 hydratio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50515558(CHEMBL4535036)
Affinity DataKi:  0.780nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50230197(CHEMBL4060402)
Affinity DataKi:  0.790nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]-CP55,940 from human CB1R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50515564(CHEMBL4535469)
Affinity DataKi:  0.800nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 preincubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50513289(CHEMBL4435918)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50513293(CHEMBL4471521)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50513282(CHEMBL4473062)
Affinity DataKi:  0.800nMAssay Description:Inhibition of human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50515303(CHEMBL4435346)
Affinity DataKi:  0.800nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50230196(CHEMBL4096350)
Affinity DataKi:  0.810nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University Of Florence

Curated by ChEMBL
LigandPNGBDBM50280336(CHEMBL4165727)
Affinity DataKi:  0.850nMAssay Description:Effect on plasma amine oxidase (0.1 uM) after 60 min of incubation at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM50515302(CHEMBL4462614)
Affinity DataKi:  0.860nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Department Of University Of Florence

Curated by ChEMBL
LigandPNGBDBM50066128(CHEMBL3402964)
Affinity DataKi:  0.860nMAssay Description:Inhibition of human recombinant CA-9 after 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Department Of University Of Florence

Curated by ChEMBL
LigandPNGBDBM50469130(CHEMBL4278541)
Affinity DataKi:  0.870nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Department Of University Of Florence

Curated by ChEMBL
LigandPNGBDBM50469136(CHEMBL4290136)
Affinity DataKi:  0.890nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Department Of University Of Florence

Curated by ChEMBL
LigandPNGBDBM50066121(CHEMBL3402971)
Affinity DataKi:  0.890nMAssay Description:Inhibition of human recombinant CA-9 after 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50589823(CHEMBL5199926)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50589828(CHEMBL5197745)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
University of Florence

Curated by ChEMBL
LigandPNGBDBM50004997(CHEMBL2392427)
Affinity DataKi:  0.900nMAssay Description:Inhibition of recombinant human CA4 pre-incubated for 15 mins by phenol red dye based stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
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