Compile Data Set for Download or QSAR
maximum 50k data
Found 16 with Last Name = 'dinter' and Initial = 'h'
TargetCannabinoid receptor 1(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50172899(3,4-diarylpyrazoline derivative | CHEMBL195050)
Affinity DataKi:  30nMAssay Description:Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50172900(3,4-diarylpyrazoline derivative | CHEMBL197040)
Affinity DataKi:  155nMAssay Description:Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50172909(3,4-diarylpyrazoline derivative | CHEMBL372650)
Affinity DataKi:  223nMAssay Description:Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50172904(3,4-diarylpyrazoline derivative | CHEMBL196989)
Affinity DataKi:  231nMAssay Description:Displacement of radioligand CP55940 from human CB1 receptor expressed in CHO cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  1.40E+3nMAssay Description:Noncompetitive inhibition of MRP1-mediated E2-17betaG transport in human MRP1 expressing HEK293 cells by Dixon plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM21278(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Affinity DataKi:  4.00E+3nMAssay Description:Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Radboud University Nijmegen Medical Centre

Curated by ChEMBL
LigandPNGBDBM50172903(3,4-diarylpyrazoline derivative | CHEMBL364300)
Affinity DataKi:  7.00E+3nMAssay Description:Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81917(BX-2819)
Affinity DataIC50:  0.0400nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81914(Ethyl carbamate analog, 3)
Affinity DataIC50:  0.100nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81916(lspropyl analog, 5)
Affinity DataIC50:  0.100nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81915(Ethyl analog, 4)
Affinity DataIC50:  0.200nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81912(DC23 | Resorcinol analog, 1)
Affinity DataIC50:  0.300nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Bayer Healthcare

LigandPNGBDBM81913(Unsubstituted phenyl ring analog, 2)
Affinity DataIC50:  0.5nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17051(BX-795 | BX-795, 3 | N-(3-{[5-iodo-4-({3-[(thiophe...)
Affinity DataIC50:  6nMpH: 7.2 T: 2°CAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17052(BX-912 | N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)et...)
Affinity DataIC50:  12nMpH: 7.2 T: 2°CAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM17053(BX-320 | N-(3-{[5-bromo-2-({3-[(pyrrolidin-1-ylcar...)
Affinity DataIC50:  39nMpH: 7.2 T: 2°CAssay Description:The coupled assay can detect inhibitors of AKT2 activation, as well as direct inhibitors of PDK1 or AKT2. Inactive AKT2 is activated in situ by incub...More data for this Ligand-Target Pair