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Found 77 with Last Name = 'ducommun' and Initial = 'b'
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50216171(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human Chk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50267086(Adociaquinone B | CHEMBL476648)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385583(CHEMBL2041917)
Affinity DataIC50:  90nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50175216(5-(2-(dimethylamino)ethylamino)-2-ethylbenzo[d]oxa...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against recombinant CDC25CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385585(CHEMBL2041919)
Affinity DataIC50:  130nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50175215(6-(2-(dimethylamino)ethylamino)-2-ethylbenzo[d]oxa...)
Affinity DataIC50:  130nMAssay Description:Inhibitory activity against recombinant CDC25CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50175218(5-(2-(dimethylamino)ethylamino)-2-methylbenzo[d]th...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against recombinant CDC25CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385583(CHEMBL2041917)
Affinity DataIC50:  180nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50216159(5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...)
Affinity DataIC50:  200nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50175219(6-(2-(dimethylamino)ethylamino)-2-phenylbenzo[d]ox...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against recombinant CDC25CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50175217(5-(2-(dimethylamino)ethylamino)-2-phenylbenzo[d]ox...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against recombinant CDC25CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50106497(6-Chloro-7-(2-morpholin-4-yl-ethylamino)-quinoline...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against recombinant CDC25CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50216159(5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...)
Affinity DataIC50:  260nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385580(CHEMBL2041914)
Affinity DataIC50:  300nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385585(CHEMBL2041919)
Affinity DataIC50:  310nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385584(CHEMBL2041918)
Affinity DataIC50:  420nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385583(CHEMBL2041917)
Affinity DataIC50:  510nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50216171(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Affinity DataIC50:  520nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385584(CHEMBL2041918)
Affinity DataIC50:  910nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50216171(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385585(CHEMBL2041919)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385579(CHEMBL2041749)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385584(CHEMBL2041918)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50264095((3-Carboxymethylsulfanyl-1,4-dioxo-1,4-dihydro-nap...)
Affinity DataIC50:  1.75E+3nMAssay Description:Inhibition of human recombinant CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385580(CHEMBL2041914)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50216171(CHEMBL393545 | pyrrolo[3',4':5,6]indolizino[8,7-b]...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50216159(5-hydroxy-pyrrolo[3',4':5,6]indolizino[8,7-b]indol...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50264096((3-Benzyloxycarbonylmethylsulfanyl-1,4-dioxo-1,4-d...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human recombinant CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385581(CHEMBL2041915)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50208827(2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione |...)
Affinity DataIC50:  3.77E+3nMAssay Description:Inhibition of human recombinant fused MBP-CDC25B3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50155597(4-Dimethylamino-2-{[2-(4-nitro-phenyl)-ethylamino]...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibitory concentration for human cell division cycle 25 degree C phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50155595(4-Dimethylamino-2-methoxy-6-{[2-(4-nitro-phenyl)-e...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration for human cell division cycle 25 degree C phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385580(CHEMBL2041914)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50264094(2-(3-methyl-1,4-dioxo-1,4-dihydronaphthalen-2-ylth...)
Affinity DataIC50:  4.13E+3nMAssay Description:Inhibition of human recombinant CDC25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50264040(3-[(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)...)
Affinity DataIC50:  4.55E+3nMAssay Description:Inhibition of human recombinant fused MBP-CDC25B3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50264041(6,7-dibromoquinoline-5,8-dione | CHEMBL488961)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human recombinant fused MBP-CDC25B3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50370437(BN-82002 | CHEMBL1258871)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibitory concentration for human cell division cycle 25 degree C phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 3(Homo sapiens (Human))
Institut Henri Beaufour

Curated by ChEMBL
LigandPNGBDBM50155599(4-Dimethylamino-2-({methyl-[2-(4-nitro-phenyl)-eth...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibitory concentration for human cell division cycle 25 degree C phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385579(CHEMBL2041749)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385579(CHEMBL2041749)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385578(CHEMBL2041912)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385582(CHEMBL2041916)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50385581(CHEMBL2041915)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385581(CHEMBL2041915)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385582(CHEMBL2041916)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50385578(CHEMBL2041912)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused rat recombinant DYRK1A expressed in Escherichia coli using Woodtide as substrate and [gamma-33P] after 30 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385582(CHEMBL2041916)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50385578(CHEMBL2041912)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50264043(3,3'-[(5,8-Dioxo-5,8-dihydroquinoline-6,7-diyl)dis...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human recombinant fused MBP-CDC25B3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50263994(CHEMBL491009 | Dibenzyl [2-(1,4-dioxo-1,4-dihydron...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of human recombinant fused MBP-CDC25B3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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