TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 0.0300nMAssay Description:Steady state and transient kinetics to a freely reversible, non-covalently bound, human recombinant Phospholipase A2 (rhLp-PLA2) was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.470nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.480nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity towards Angiotensin I converting enzyme of rat brain IgG immobilized enzyme.More data for this Ligand-Target Pair
Affinity DataKi: 0.5nM ΔG°: -52.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.780nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.790nM ΔG°: -51.4kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 0.790nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.810nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.840nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity of the compound to the human Neuropeptide Y receptor type 5 was determined using [125I]- [PYY] as radioligandMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.58nM ΔG°: -49.7kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using [125I]-PYY as radiogigand in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Binding affinity of the compound to the rat Neuropeptide Y receptor type 5 was determined using [125I]- [Leu31,Pro34]PYY as radioligandMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nM ΔG°: -48.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nMAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2.51nM ΔG°: -48.6kJ/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.60nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Binding affinity to PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 2.80nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Binding affinity against neuronal nicotinic acetylcholine receptor(nAChR) by using [3H]-Cytisine as radioligand in whole rat brainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition of HPK1 (unknown origin) followed by anti-GST antibody incubated for 60 mins measured after 1 hr by TR-FRET based LanthaScreen Eu-Kinase b...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Binding affinity towards human neuropeptide Y receptor type 5 using 125[I]-PYY as radioligandMore data for this Ligand-Target Pair