Affinity DataKi: 100nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 190nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
Affinity DataKi: 940nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 1.04E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
Affinity DataKi: 1.22E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 5.40E+3nMAssay Description:Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 6.70E+3nMAssay Description:Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
Affinity DataKi: 6.76E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 8.98E+3nMAssay Description:Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 1.09E+4nMAssay Description:Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 1.18E+4nMAssay Description:Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 1.39E+4nMAssay Description:Kinetic inhibition constant of compound with bacterial Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nM ΔG°: -27.9kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nM ΔG°: -27.8kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: >2.50E+4nMAssay Description:Kinetic inhibition constant of compound with bacterial Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nM ΔG°: -27.0kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 2.88E+4nMAssay Description:Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nM ΔG°: -26.9kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
University Of Connecticut
Curated by ChEMBL
University Of Connecticut
Curated by ChEMBL
Affinity DataKi: 4.81E+4nMAssay Description:Kinetic inhibition constant of compound with bacterial Hypoxanthine Phosphoribosyltransferase (HPRT)More data for this Ligand-Target Pair
Affinity DataKi: 8.50E+4nM ΔG°: -24.2kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 2.43E+5nM ΔG°: -21.5kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 1.88E+6nM ΔG°: -16.2kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+6nM ΔG°: -15.8kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 4.90E+6nM ΔG°: -13.7kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 1.25E+7nM ΔG°: -11.3kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+7nM ΔG°: -10.3kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 1.82E+7nM ΔG°: -10.3kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 1.88E+7nM ΔG°: -10.2kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 2.29E+7nM ΔG°: -9.74kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 2.45E+7nM ΔG°: -9.56kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 3.64E+7nM ΔG°: -8.54kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 3.84E+7nM ΔG°: -8.41kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 4.49E+7nM ΔG°: -8.00kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: >1.50E+8nM ΔG°: >-4.89kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataKi: 2.23E+8nM ΔG°: -3.87kJ/molepH: 8.1 T: 2°CAssay Description:The PBGS assay is a colorimetric assay based on the reaction between PBG and 4-dimethylaminobenzaldehyde (Ehrlich's reagent). More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi Deutschland
Curated by ChEMBL
Sanofi Deutschland
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi Deutschland
Curated by ChEMBL
Sanofi Deutschland
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair