Compile Data Set for Download or QSAR
maximum 50k data
Found 51 with Last Name = 'fabian' and Initial = 'j'
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50346387(CHEMBL1783450 | cis-rac-N-Benzyl-2-(2-phenyl-1,3-d...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397373(CHEMBL2170313)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397372(CHEMBL2170314)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50346393(CHEMBL1783458 | trans-N-Benzyl-2-(2-ethyl-2-phenyl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397371(CHEMBL2170178)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397374(CHEMBL2170312)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397369(CHEMBL2170180)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397367(CHEMBL2170302)
Affinity DataKi:  128nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397370(CHEMBL2170179)
Affinity DataKi:  136nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397368(CHEMBL2170301)
Affinity DataKi:  253nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50346384(CHEMBL1783426 | cis-rac-2-(2-Phenyl-1,3-dioxan-4-y...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397375(CHEMBL2170311)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397376(CHEMBL2170310)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397377(CHEMBL2170309)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397378(CHEMBL2170308)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50346390(CHEMBL1783455 | trans-2-(2-Ethyl-2-phenyl-1,3-diox...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397379(CHEMBL2170307)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397380(CHEMBL2170306)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397381(CHEMBL2170305)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50397382(CHEMBL2170315)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50346390(CHEMBL1783455 | trans-2-(2-Ethyl-2-phenyl-1,3-diox...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50346384(CHEMBL1783426 | cis-rac-2-(2-Phenyl-1,3-dioxan-4-y...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  18nMAssay Description:Inhibition of cPLA2-alpha in TPA-stimulated intact human platelets assessed as liberation of arachidonic acid after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50185356(1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50361331(CHEMBL1933276)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376192(CHEMBL260247)
Affinity DataIC50:  300nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376191(CHEMBL260248)
Affinity DataIC50:  300nMAssay Description:Inhibition of cPLA2-alpha in TPA-stimulated intact human platelets assessed as liberation of arachidonic acid after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376191(CHEMBL260248)
Affinity DataIC50:  400nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376190(CHEMBL260708)
Affinity DataIC50:  500nMAssay Description:Inhibition of cPLA2-alpha in TPA-stimulated intact human platelets assessed as liberation of arachidonic acid after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376190(CHEMBL260708)
Affinity DataIC50:  600nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50361332(CHEMBL1933420)
Affinity DataIC50:  600nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376187(CHEMBL260365)
Affinity DataIC50:  600nMAssay Description:Inhibition of cPLA2-alpha in TPA-stimulated intact human platelets assessed as liberation of arachidonic acid after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50273710(2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...)
Affinity DataIC50:  650nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  670nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  800nMAssay Description:Inhibition of mPGES-1 in human A549 cell microsomes assessed as conversion of PGH2 into PGE2 at 0 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50060279(3-(4-Dodecanoyl-1,3,5-trimethyl-1H-pyrrol-2-yl)-pr...)
Affinity DataIC50:  800nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376187(CHEMBL260365)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376192(CHEMBL260247)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of cPLA2-alpha in TPA-stimulated intact human platelets assessed as liberation of arachidonic acid after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant mPGES-1 in assessed as conversion of PGH2 into PGE2 at 20 degC after 5 mins by HPLC-UV analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376189(CHEMBL260517)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50006805(3-(1-(4-chlorobenzyl)-3-(tert-butylthio)-5-isoprop...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376195(CHEMBL258651)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50059523((6Z,9Z,12Z,15Z)-1,1,1-trifluorohenicosa-6,9,12,15-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376186(CHEMBL259823)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376194(CHEMBL260716)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376188(CHEMBL410658)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of mPGES-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytosolic phospholipase A2(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL
LigandPNGBDBM50376193(CHEMBL409357)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human platelet cPLA2-alpha activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 51 total ) | Next | Last >>
Jump to: