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Found 34 with Last Name = 'fabre' and Initial = 'm'
LigandPNGBDBM50199036(4-[(5S,9R)-3-(3,5-dichloro-phenyl)-1-methyl-2,4-di...)
Affinity DataIC50:  3nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50199031(4-[(5S,9R)-3-(3,5-dichloro-phenyl)-1-methyl-2,4-di...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50199037(4-[(5S,9R)-3-(3,5-dichloro-phenyl)-1-methyl-2,4-di...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303132(US10137202, Compound TAM552)
Affinity DataIC50:  10nMAssay Description:cell proliferation arrest on HT1080 cells (CPA; crystal violet).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50199030(4-[(5S,9R)-9-(4-cyano-phenyl)-3-(3,5-dichloro-phen...)
Affinity DataIC50:  12nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50199035(4-[(5S,9R)-3-(3,5-dichloro-phenyl)-7-isobutyl-1-me...)
Affinity DataIC50:  14nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50199039(4-[(5S,9R)-7-benzyl-3-(3,5-dichloro-phenyl)-1-meth...)
Affinity DataIC50:  15nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50199033(5-[(5S,9R)-9-(4-CYANOPHENYL)-3-(3,5-DICHLOROPHENYL...)
Affinity DataIC50:  20nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
LigandPNGBDBM50199033(5-[(5S,9R)-9-(4-CYANOPHENYL)-3-(3,5-DICHLOROPHENYL...)
Affinity DataIC50:  21nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50154496((R)-5-(4-Bromo-benzyl)-3-(3,5-dichloro-phenyl)-1,5...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303131(US10137202, Compound TAM471)
Affinity DataIC50:  29.5nMAssay Description:cell proliferation arrest on HT1080 cells (CPA; crystal violet).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50199038(4-[(5S,9R)-9-(4-cyano-phenyl)-3-(3,5-dichloro-phen...)
Affinity DataIC50:  30nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160927((6S,7aS)-6-(4''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...)
Affinity DataIC50:  85nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303130(US10137202, Compound TAM551)
Affinity DataIC50:  90nMAssay Description:cell proliferation arrest on HT1080 cells (CPA; crystal violet).More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303139(US10137202, Compound TAM558)
Affinity DataIC50:  98nMAssay Description:cell proliferation arrest on HT1080 cells (CPA; crystal violet).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303138(US10137202, Compound TAM553)
Affinity DataIC50:  98nMAssay Description:cell proliferation arrest on HT1080 cells (CPA; crystal violet).More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM50199032(4-[(5S,9R)-9-(4-cyano-phenyl)-3-(3,5-dichloro-phen...)
Affinity DataIC50:  164nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160919((6S,7aS)-6-[(4''-Bromo-biphenyl-3-ylmethyl)-methyl...)
Affinity DataIC50:  175nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160925(3''-{[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-h...)
Affinity DataIC50:  175nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160924(3''-[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-he...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160920((6R,7aS)-6-(4''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...)
Affinity DataIC50:  275nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160929((6S,7aS)-6-(4''-Bromo-biphenyl-3-ylmethylsulfanyl)...)
Affinity DataIC50:  290nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50199034(5-[(5R,9S)-9-(4-cyano-phenyl)-3-(3,5-dichloro-phen...)
Affinity DataIC50:  320nMAssay Description:Inhibition of LFA1-mediated adhesion of T cell to HUVECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303129(US10137202, Compound TAM467)
Affinity DataIC50:  325nMAssay Description:cell proliferation arrest on HT1080 cells (CPA; crystal violet).More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160923((6S,7aS)-6-(4''-Bromo-biphenyl-4-yloxy)-2-(3,5-dic...)
Affinity DataIC50:  480nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160928((6R,7aR)-6-(4''-Chloro-biphenyl-3-ylmethoxy)-2-(3,...)
Affinity DataIC50:  620nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160926(3''-({[(6S,7aS)-2-(3,5-Dichloro-phenyl)-1,3-dioxo-...)
Affinity DataIC50:  730nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160921((6S,7aS)-6-(3''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...)
Affinity DataIC50:  755nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Cerep

Curated by ChEMBL
LigandPNGBDBM50160920((6R,7aS)-6-(4''-Bromo-biphenyl-3-ylmethoxy)-2-(3,5...)
Affinity DataIC50:  935nMAssay Description:Inhibitory concentration against leukocyte function-associated antigen-1 in HSB-2 human lymphoblast and H1HeLa cell adhesion assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303132(US10137202, Compound TAM552)
Affinity DataIC50:  1.90E+3nMAssay Description:TPI; Tubulin Polymerization assay kit; Cytoskeleton, Cat. #BK011P.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303139(US10137202, Compound TAM558)
Affinity DataIC50:  1.90E+3nMAssay Description:TPI; Tubulin Polymerization assay kit; Cytoskeleton, Cat. #BK011P.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303138(US10137202, Compound TAM553)
Affinity DataIC50:  6.00E+3nMAssay Description:TPI; Tubulin Polymerization assay kit; Cytoskeleton, Cat. #BK011P.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303131(US10137202, Compound TAM471)
Affinity DataIC50:  1.40E+4nMAssay Description:TPI; Tubulin Polymerization assay kit; Cytoskeleton, Cat. #BK011P.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Oncomatryx Biopharma

US Patent
LigandPNGBDBM303129(US10137202, Compound TAM467)
Affinity DataIC50:  1.50E+5nMAssay Description:TPI; Tubulin Polymerization assay kit; Cytoskeleton, Cat. #BK011P.More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent