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Found 111 with Last Name = 'fei' and Initial = 'xs'
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109929(7-({2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-eth...)
Affinity DataKi:  1.10nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931((+)-7-{[4-(4-phenylpiperazin-1-yl)butyl]prop-2-yny...)
Affinity DataKi:  1.40nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109926(7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)...)
Affinity DataKi:  1.80nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109930(7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but...)
Affinity DataKi:  2.30nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109925(7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but...)
Affinity DataKi:  3.60nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((+)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  3.80nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109925(7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but...)
Affinity DataKi:  7.40nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109930(7-({4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but...)
Affinity DataKi:  8.80nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109928(7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-prop-2-ynyl...)
Affinity DataKi:  14nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109929(7-({2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-eth...)
Affinity DataKi:  27nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109923(4-{(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  50nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109922(CHEMBL422883 | N-(2-{(7-Hydroxy-1,2,3,4-tetrahydro...)
Affinity DataKi:  56nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109931((+)-7-{[4-(4-phenylpiperazin-1-yl)butyl]prop-2-yny...)
Affinity DataKi:  68nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109927((+)-7-[(4-(4-phenylpiperazin-1-yl)butyl)(propyl)am...)
Affinity DataKi:  114nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109926(7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)...)
Affinity DataKi:  213nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109928(7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-prop-2-ynyl...)
Affinity DataKi:  245nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109922(CHEMBL422883 | N-(2-{(7-Hydroxy-1,2,3,4-tetrahydro...)
Affinity DataKi:  354nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109923(4-{(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-...)
Affinity DataKi:  622nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109924(CHEMBL156816 | N-(4-{(7-Hydroxy-1,2,3,4-tetrahydro...)
Affinity DataKi:  756nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D3 in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50109924(CHEMBL156816 | N-(4-{(7-Hydroxy-1,2,3,4-tetrahydro...)
Affinity DataKi:  782nMAssay Description:Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108815(4-(2-Benzhydryloxy-ethyl)-1-(4-iodo-benzyl)-piperi...)
Affinity DataIC50:  0.960nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108818(4-(2-Benzhydryloxy-ethyl)-1-(4-vinyl-benzyl)-piper...)
Affinity DataIC50:  2.96nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098393(4-[4-(2-Benzhydryloxy-ethyl)-piperidin-1-ylmethyl]...)
Affinity DataIC50:  3.67nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108817(4-(2-Benzhydryloxy-ethyl)-1-(4-ethynyl-benzyl)-pip...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098396(Benzhydryl-[2-(1-benzyl-piperidin-4-yl)-ethyl]-ami...)
Affinity DataIC50:  4.5nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098396(Benzhydryl-[2-(1-benzyl-piperidin-4-yl)-ethyl]-ami...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098395(Benzhydryl-{2-[1-(3,4-difluoro-benzyl)-piperidin-4...)
Affinity DataIC50:  7nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108823(4-[4-(2-Benzhydryloxy-ethyl)-piperidin-1-ylmethyl]...)
Affinity DataIC50:  8.23nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50066414(Benzhydryl-{2-[1-(4-fluoro-benzyl)-piperidin-4-yl]...)
Affinity DataIC50:  9.37nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098397(4-(2-Benzhydryloxy-ethyl)-1-(3,4-difluoro-benzyl)-...)
Affinity DataIC50:  10.1nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  10.6nMAssay Description:Inhibition of binding of 3[H] WIN-35 428 to Dopamine transporter (DAT) of rat striatum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  10.6nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108820(4-(2-Benzhydryloxy-ethyl)-1-(4-isopropenyl-benzyl)...)
Affinity DataIC50:  11.6nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108821(3-[4-(2-Benzhydryloxy-ethyl)-piperidin-1-ylmethyl]...)
Affinity DataIC50:  14.3nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50055876(4-(2-Benzhydryloxy-ethyl)-1-(4-fluoro-benzyl)-pipe...)
Affinity DataIC50:  17.2nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108824(4-(2-Benzhydryloxy-ethyl)-1-(3-methoxy-benzyl)-pip...)
Affinity DataIC50:  19.6nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098392((2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidi...)
Affinity DataIC50:  19.7nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098399(4-(2-Benzhydryloxy-ethyl)-1-(3-fluoro-benzyl)-pipe...)
Affinity DataIC50:  23.4nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098394(CHEMBL353643 | N-{4-[4-(2-Benzhydryloxy-ethyl)-pip...)
Affinity DataIC50:  26.6nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108819(4-(2-Benzhydryloxy-ethyl)-1-(4-naphthalen-2-yl-ben...)
Affinity DataIC50:  26.9nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098405(4-(2-Benzhydryloxy-ethyl)-1-(4-trifluoromethyl-ben...)
Affinity DataIC50:  32.1nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098404(CHEMBL424005 | O-Benzhydryl-N-[1-(4-fluoro-benzyl)...)
Affinity DataIC50:  34.4nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108816(3-(2-Benzhydryloxy-ethyl)-1-(4-isopropyl-benzyl)-p...)
Affinity DataIC50:  63.1nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108822(4-(2-Benzhydryloxy-ethyl)-1-(4-prop-1-ynyl-benzyl)...)
Affinity DataIC50:  65.1nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098402(CHEMBL173812 | [Bis-(4-fluoro-phenyl)-methyl]-(1-p...)
Affinity DataIC50:  65.3nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098401((2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidi...)
Affinity DataIC50:  94nMAssay Description:In vitro binding affinity at dopamine transporter in rat striatum by [3H]WIN-35428 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50108825(4-(2-Benzhydryloxy-ethyl)-1-(4-naphthalen-1-yl-ben...)
Affinity DataIC50:  113nMAssay Description:Inhibition of 3[H] WIN-35 428 binding to Dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  132nMAssay Description:In vitro binding affinity at serotonin transporter in rat striatum by [3H]- citalopram displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM22165(1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-pheny...)
Affinity DataIC50:  132nMAssay Description:Inhibition of binding of [3H]- citalopram to Serotonin transporter (SERT) of rat cerebral cortex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50098392((2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidi...)
Affinity DataIC50:  137nMAssay Description:In vitro binding affinity at serotonin transporter in rat striatum by [3H]- citalopram displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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