Compile Data Set for Download or QSAR
maximum 50k data
Found 48 with Last Name = 'flatt' and Initial = 'b'
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28529(Azepino[4,5-b]indole, 1 | ethyl 3-[(4-fluorophenyl...)
Affinity DataEC50:  600nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  28nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28531(Azepino[4,5-b]indole, 6b | propyl 3-[(4-fluorophen...)
Affinity DataEC50:  500nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28532(Azepino[4,5-b]indole, 6c | butyl 3-[(4-fluoropheny...)
Affinity DataEC50:  1.10E+3nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28533(Azepino[4,5-b]indole, 6d | ethyl 3-[(4-fluoropheny...)
Affinity DataEC50:  57nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28534(Azepino[4,5-b]indole, 6e | ethyl 3-[(4-chloropheny...)
Affinity DataEC50:  73nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28535(Azepino[4,5-b]indole, 6f | ethyl 3-[(4-methoxyphen...)
Affinity DataEC50:  60nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28536(Azepino[4,5-b]indole, 6g | ethyl 3-[(3,4-difluorop...)
Affinity DataEC50:  32nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28537(Azepino[4,5-b]indole, 6h | ethyl 3-[(4-fluoropheny...)
Affinity DataEC50:  22nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28538(Azepino[4,5-b]indole, 6i | FXR_5 | ethyl 3-[(3,4-d...)
Affinity DataEC50:  12nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28539(Azepino[4,5-b]indole, 6j | ethyl 3-[(4-chloropheny...)
Affinity DataEC50:  25nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28540(Azepino[4,5-b]indole, 6k | ethyl 3-[(4-methoxyphen...)
Affinity DataEC50:  29nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28541(Azepino[4,5-b]indole, 6l | propan-2-yl 3-[(4-fluor...)
Affinity DataEC50:  8nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28542(WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...)
Affinity DataEC50:  4nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034775(CHEMBL3360975 | US10543183, Compound 38 | US109459...)
Affinity DataEC50:  250nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034776(CHEMBL3360974)
Affinity DataEC50:  66nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034777(CHEMBL3360973)
Affinity DataEC50:  140nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034778(CHEMBL3360972)
Affinity DataEC50:  670nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034779(CHEMBL3360971)
Affinity DataEC50:  600nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034780(CHEMBL3360970)
Affinity DataEC50:  61nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034781(CHEMBL3360969)
Affinity DataEC50:  620nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034782(CHEMBL3360968)
Affinity DataEC50:  64nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034783(CHEMBL3360967)
Affinity DataEC50:  230nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034784(CHEMBL3360966)
Affinity DataEC50:  49nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034785(CHEMBL3360965)
Affinity DataEC50:  68nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034786(CHEMBL3360964)
Affinity DataEC50:  110nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034788(CHEMBL3360963)
Affinity DataEC50:  14nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034789(CHEMBL3360962)
Affinity DataEC50:  320nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034790(CHEMBL3360961)
Affinity DataEC50:  20nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034791(CHEMBL3360960)
Affinity DataEC50:  2nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM19993(CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataEC50:  140nMAssay Description:Transactivation of LXRbeta (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034775(CHEMBL3360975 | US10543183, Compound 38 | US109459...)
Affinity DataEC50:  230nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034776(CHEMBL3360974)
Affinity DataEC50:  85nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034777(CHEMBL3360973)
Affinity DataEC50:  200nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034778(CHEMBL3360972)
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034779(CHEMBL3360971)
Affinity DataEC50: >1.00E+4nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034780(CHEMBL3360970)
Affinity DataEC50:  52nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034781(CHEMBL3360969)
Affinity DataEC50:  540nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034782(CHEMBL3360968)
Affinity DataEC50:  65nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034783(CHEMBL3360967)
Affinity DataEC50:  320nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034784(CHEMBL3360966)
Affinity DataEC50:  220nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034785(CHEMBL3360965)
Affinity DataEC50:  120nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034786(CHEMBL3360964)
Affinity DataEC50:  140nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034788(CHEMBL3360963)
Affinity DataEC50:  18nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034789(CHEMBL3360962)
Affinity DataEC50:  570nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034790(CHEMBL3360961)
Affinity DataEC50:  20nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50034791(CHEMBL3360960)
Affinity DataEC50:  4nMAssay Description:Transactivation of LXRalpha (unknown origin) expressed in CV1 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Homo sapiens (Human))
Exelixis

LigandPNGBDBM28530(Azepino[4,5-b]indole, 6a | propan-2-yl 3-[(4-fluor...)
Affinity DataEC50:  500nMpH: 7.0 T: 2°CAssay Description:The assays were performed using CV-1 African Green Monkey Kidney cells transfected with the vectors harboring human FXR, RXR, and luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed