Compile Data Set for Download or QSAR
maximum 50k data
Found 236 with Last Name = 'fong' and Initial = 'd'
LigandPNGBDBM50396616(CHEMBL2171930 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  3nMAssay Description:Inhibition of PI3Kdelta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396610(CHEMBL2171929 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataKi:  7nMAssay Description:Inhibition of PI3Kdelta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396611(CHEMBL2171927 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  10nMAssay Description:Inhibition of PI3Kdelta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396614(CHEMBL2171931 | US8765940, 1'-(7-fluoro-3-meth...)
Affinity DataKi:  11nMAssay Description:Inhibition of PI3Kdelta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396616(CHEMBL2171930 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  18nMAssay Description:Inhibition of PI3Kbeta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396616(CHEMBL2171930 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  28nMAssay Description:Inhibition of PI3Kgamma by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396610(CHEMBL2171929 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataKi:  30nMAssay Description:Inhibition of PI3Kbeta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396614(CHEMBL2171931 | US8765940, 1'-(7-fluoro-3-meth...)
Affinity DataKi:  44nMAssay Description:Inhibition of PI3Kbeta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396611(CHEMBL2171927 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  54nMAssay Description:Inhibition of PI3Kbeta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396613(CHEMBL2171924 | US8765940, 1-(7-fluoro-3-methyl-2-...)
Affinity DataKi:  80nMAssay Description:Inhibition of PI3Kdelta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396611(CHEMBL2171927 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  90nMAssay Description:Inhibition of PI3Kgamma by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396610(CHEMBL2171929 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataKi:  92nMAssay Description:Inhibition of PI3Kgamma by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396617(CHEMBL2171925 | US8765940, (1-(7-fluoro-3-methyl-2...)
Affinity DataKi:  154nMAssay Description:Inhibition of PI3Kdelta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396617(CHEMBL2171925 | US8765940, (1-(7-fluoro-3-methyl-2...)
Affinity DataKi:  269nMAssay Description:Inhibition of PI3Kbeta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396615(CHEMBL2171928 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  364nMAssay Description:Inhibition of PI3Kgamma by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396613(CHEMBL2171924 | US8765940, 1-(7-fluoro-3-methyl-2-...)
Affinity DataKi:  395nMAssay Description:Inhibition of PI3Kbeta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396615(CHEMBL2171928 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  449nMAssay Description:Inhibition of PI3Kdelta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396614(CHEMBL2171931 | US8765940, 1'-(7-fluoro-3-meth...)
Affinity DataKi:  509nMAssay Description:Inhibition of PI3Kgamma by ATP bioluminescence assayMore data for this Ligand-Target Pair
LigandPNGBDBM50396616(CHEMBL2171930 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  510nMAssay Description:Inhibition of PI3Kalpha by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396610(CHEMBL2171929 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataKi:  1.72E+3nMAssay Description:Inhibition of PI3Kalpha by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396614(CHEMBL2171931 | US8765940, 1'-(7-fluoro-3-meth...)
Affinity DataKi:  3.25E+3nMAssay Description:Inhibition of PI3Kalpha by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396611(CHEMBL2171927 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi:  3.54E+3nMAssay Description:Inhibition of PI3Kalpha by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396613(CHEMBL2171924 | US8765940, 1-(7-fluoro-3-methyl-2-...)
Affinity DataKi:  7.34E+3nMAssay Description:Inhibition of PI3Kgamma by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396613(CHEMBL2171924 | US8765940, 1-(7-fluoro-3-methyl-2-...)
Affinity DataKi: >1.25E+4nMAssay Description:Inhibition of PI3Kalpha by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396617(CHEMBL2171925 | US8765940, (1-(7-fluoro-3-methyl-2...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of PI3Kgamma by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396615(CHEMBL2171928 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi: >1.25E+5nMAssay Description:Inhibition of PI3Kalpha by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396615(CHEMBL2171928 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataKi: >1.25E+5nMAssay Description:Inhibition of PI3Kbeta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396617(CHEMBL2171925 | US8765940, (1-(7-fluoro-3-methyl-2...)
Affinity DataKi: >1.25E+5nMAssay Description:Inhibition of PI3Kalpha by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  0.0210nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  0.0410nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14774(3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...)
Affinity DataIC50:  0.680nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14774(3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...)
Affinity DataIC50:  0.840nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase [531-875](Homo sapiens (Human))
Plexxikon

LigandPNGBDBM14776(2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phen...)
Affinity DataIC50:  1nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase [531-875](Homo sapiens (Human))
Plexxikon

LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)
Affinity DataIC50:  1.20nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase [531-875](Homo sapiens (Human))
Plexxikon

LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  2.20nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM50396616(CHEMBL2171930 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of PI3Kdelta in human B cells assessed as inhibition of anti-IgM/CD40L-induced proliferation after 72 hrs by [3H]thymidine incorporation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396610(CHEMBL2171929 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PI3Kdelta in human B cells assessed as inhibition of anti-IgM/CD40L-induced proliferation after 72 hrs by [3H]thymidine incorporation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396614(CHEMBL2171931 | US8765940, 1'-(7-fluoro-3-meth...)
Affinity DataIC50:  9nMAssay Description:Inhibition of PI3Kdelta in human B cells assessed as inhibition of anti-IgM/CD40L-induced proliferation after 72 hrs by [3H]thymidine incorporation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396616(CHEMBL2171930 | US8765940, 4-(1-(7-fluoro-3-methyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3Kbeta-mediated AKT Ser473 phosphorylation in human MDA-MB-468 cells after 120 mins by meso scale discover assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)
Affinity DataIC50:  10nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14773(4-cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)cyclo...)
Affinity DataIC50:  11nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Plexxikon

LigandPNGBDBM25617(N-[3-({5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl}carb...)
Affinity DataIC50:  13nMpH: 7.0 T: 2°CAssay Description:The in vitro kinase activities of wild type or mutants were determined by measuring phosphorylation of biotinylated-MEK protein using Perkin-Elmer s ...More data for this Ligand-Target Pair
LigandPNGBDBM50396626(CHEMBL2171920 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataIC50:  17nMAssay Description:Inhibition of PI3Kdelta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14797(Pyrazole carboxylic ester 20 | ethyl 1-(2-chloroph...)
Affinity DataIC50:  19nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14798(Pyrazole carboxylic ester 21 | ethyl 3,5-dimethyl-...)
Affinity DataIC50:  21nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM14773(4-cyano-4-(3-cyclopentyloxy-4-methoxy-phenyl)cyclo...)
Affinity DataIC50:  25nMAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM50396618(CHEMBL2171918 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataIC50:  30nMAssay Description:Inhibition of PI3Kdelta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14798(Pyrazole carboxylic ester 21 | ethyl 3,5-dimethyl-...)
Affinity DataIC50:  33nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase activities were assayed in the presence of inhibitor compounds. Measurement takes advantage of the selective binding of 5-AMP or 5-...More data for this Ligand-Target Pair
LigandPNGBDBM50396621(CHEMBL2171935 | US8765940, 4-(3,3-dimethyl-6-(4-mo...)
Affinity DataIC50:  35nMAssay Description:Inhibition of PI3Kbeta using phosphatidylinositol-4,5-bisphosphate by ATP bioluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50396614(CHEMBL2171931 | US8765940, 1'-(7-fluoro-3-meth...)
Affinity DataIC50:  36nMAssay Description:Inhibition of PI3Kbeta-mediated AKT Ser473 phosphorylation in human MDA-MB-468 cells after 120 mins by meso scale discover assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 236 total ) | Next | Last >>
Jump to: