Affinity DataKi: 240nMAssay Description:Inhibition of human supersomes CYP1A1-mediated 7-ethoxyresorufin conversion to fluorescent resorufin preincubated with 7-ethoxyresorufin for 5 mins f...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Binding affinity to recombinant CYP1A1 in human liver microsomes assessed as inhibition constant measured for 15 mins in the presence of NADPH regene...More data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Inhibition of human supersomes CYP1A1-mediated 7-ethoxyresorufin conversion to fluorescent resorufin preincubated with 7-ethoxyresorufin for 5 mins f...More data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Binding affinity to recombinant CYP1A1 in human liver microsomes assessed as inhibition constant measured for 15 mins in the presence of NADPH regene...More data for this Ligand-Target Pair
Affinity DataKi: 540nMAssay Description:Inhibition of human supersomes CYP1A1-mediated 7-ethoxyresorufin conversion to fluorescent resorufin preincubated with 7-ethoxyresorufin for 5 mins f...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Binding affinity to recombinant CYP1A1 in human liver microsomes assessed as inhibition constant measured for 15 mins in the presence of NADPH regene...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
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Curated by ChEMBL
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Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant N-terminal His-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli using L-DHO as substrate measured ever...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of recombinant N-terminal His-tagged human DHODH (31 to 395 residues) expressed in Escherichia coli using L-DHO as substrate measured ever...More data for this Ligand-Target Pair