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Found 18 with Last Name = 'götte' and Initial = 'm'
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Mcgill University

LigandPNGBDBM92703(Indopy-1)
Affinity DataIC50:  19.7nMpH: 7.8 T: 2°CAssay Description:Inhibition assay using HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  174nMAssay Description:Displacement of 50 uM PPi from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  258nMAssay Description:Displacement of 0.1 uM UTP from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  302nMAssay Description:Displacement of 100 uM PPi from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50: >500nMAssay Description:Displacement of 1 uM UTP from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  730nMAssay Description:Inhibition of NS5B-mediated RNA synthesis in Hepatitis C virus assessed as decrease in formation of full-length product after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Mcgill University

LigandPNGBDBM92703(Indopy-1)
Affinity DataIC50:  843nMpH: 7.8 T: 2°CAssay Description:Inhibition assay using HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50:  882nMAssay Description:Displacement of 500 uM PPi from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50183494(2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of 5 uM UTP from NS5B in Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Mcgill University

LigandPNGBDBM92703(Indopy-1)
Affinity DataIC50:  1.12E+3nMpH: 7.8 T: 2°CAssay Description:Inhibition assay using HIV-1 reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  2.00E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [613-1167,R896S,E946D,S1117V]/[618-1043,R896S,E946D](Human immunodeficiency virus type 2)
National Cancer Institute-Bethesda

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  2.50E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [600-1029,C879S]/[600-1159,C879S](Human immunodeficiency virus type 1)
National Cancer Institute-Bethesda

LigandPNGBDBM33963(vinylogous urea, NSC727448)
Affinity DataIC50:  3.20E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [613-1167,R896S,E946D,S1117V]/[618-1043,R896S,E946D](Human immunodeficiency virus type 2)
National Cancer Institute-Bethesda

LigandPNGBDBM33963(vinylogous urea, NSC727448)
Affinity DataIC50:  5.00E+3nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  1.06E+4nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33963(vinylogous urea, NSC727448)
Affinity DataIC50:  2.90E+4nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease HI(Escherichia coli (strain K12))
National Cancer Institute-Bethesda

LigandPNGBDBM33963(vinylogous urea, NSC727448)
Affinity DataIC50:  7.30E+4nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease HI(Escherichia coli (strain K12))
National Cancer Institute-Bethesda

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  1.00E+5nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed