Affinity DataKi: 2.70nMAssay Description:Binding affinity of the compound against [125I]-Try0-o-Corticotropin-releasing Factor to Corticotropin releasing hormone receptor 1 from ovineMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of binding of [125I]-Tyr0-sauvagine to Corticotropin releasing hormone receptor 2 (CRF2)More data for this Ligand-Target Pair
Affinity DataIC50: 0.350nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.18nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.68nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.84nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Affinity DataIC50: 1.91nMpH: 7.4 T: 2°CAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC5 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 2.36nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.43nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 3.27nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.28nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.42nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.46nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.54nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.61nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 3.77nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.78nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.02nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.19nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.27nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.37nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.51nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.67nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.99nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of binding of 70 pM [125I]-Try0-o-Corticotropin-releasing Factor (CFR) to Corticotropin releasing hormone receptor 1 in Rat brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 5.53nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 5.73nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.22nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 6.59nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 6.82nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Affinity DataIC50: 7.49nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair