Compile Data Set for Download or QSAR
maximum 50k data
Found 256 with Last Name = 'gallaschun' and Initial = 'r'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity of the compound against [125I]-Try0-o-Corticotropin-releasing Factor to Corticotropin releasing hormone receptor 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of binding of [125I]-Tyr0-sauvagine to Corticotropin releasing hormone receptor 2 (CRF2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246181((2-(3,4-dichlorophenoxy)phenyl)-N,N-dimethylmethan...)
Affinity DataIC50:  0.350nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246445(US9447114, 1)
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246466(US9447114, 27)
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246465(US9447114, 26)
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246446(US9447114, 2)
Affinity DataIC50: <1nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246186(CHEMBL450714 | N,N-dimethyl-1-(2-(4-(methylthio)ph...)
Affinity DataIC50:  1nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246480(1-(4-chloro-2-(p-tolyloxy)phenyl)-N-methylmethanam...)
Affinity DataIC50:  1.18nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50233471((2-(4-chlorophenoxy)phenyl)-N,N-dimethylmethanamin...)
Affinity DataIC50:  1.68nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246463(US9447114, 24)
Affinity DataIC50:  1.84nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
Hydra Biosciences

US Patent
LigandPNGBDBM246465(US9447114, 26)
Affinity DataIC50:  1.91nMpH: 7.4 T: 2°CAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC5 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20954(2-(4-methoxy-2,6-dimethylphenoxy)-3,6-dimethyl-4-(...)
Affinity DataIC50:  2nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246323(1-(2-(3,4-dichlorophenoxy)-5-methylphenyl)-N,N-dim...)
Affinity DataIC50:  2.36nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246185(2-(4-(3,4-dichlorophenoxy)-3-((dimethylamino)methy...)
Affinity DataIC50:  2.43nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246372(4-(3,4-dichlorophenoxy)-3-((methylamino)methyl)ben...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20950(2-(4-bromo-2,6-dimethylphenoxy)-3,6-dimethyl-4-(pe...)
Affinity DataIC50:  2.60nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20959(2-Aryloxy-4-alkoxy-pyridine, 40 | 2-[4-(methoxymet...)
Affinity DataIC50:  3.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246229(1-(2-(3,4-dichlorophenoxy)phenyl)-N,N-dimethyletha...)
Affinity DataIC50:  3.27nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246182(1-(2-(3,4-dichlorophenoxy)-5-fluorophenyl)-N-methy...)
Affinity DataIC50:  3.28nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246134(1-(4-chloro-2-(3,4-dimethylphenoxy)phenyl)-N-methy...)
Affinity DataIC50:  3.42nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246230(CHEMBL454288 | N,N-dimethyl-1-(2-(p-tolyloxy)pheny...)
Affinity DataIC50:  3.46nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246532(1-(4-chloro-2-(p-tolyloxy)phenyl)-N-methylethanami...)
Affinity DataIC50:  3.54nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246371(1-(2-(3,4-dichlorophenoxy)-4-methoxyphenyl)-N,N-di...)
Affinity DataIC50:  3.61nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20971(2-Arylamino-4-alkyloxypyridine, 13 | 3,6-dimethyl-...)
Affinity DataIC50:  3.70nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246320(1-(2-(3,4-dichlorophenoxy)-5-methoxyphenyl)-N-meth...)
Affinity DataIC50:  3.77nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246376(4-(3,4-dichlorophenoxy)-3-((methylamino)methyl)ben...)
Affinity DataIC50:  3.78nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246184(1-(2-(3,4-dichlorophenoxy)phenyl)-N-methylmethanam...)
Affinity DataIC50:  4.02nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246537(1-(4-chloro-2-(3-chloro-4-methylphenoxy)phenyl)-N-...)
Affinity DataIC50:  4.19nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245791(1-(4-chloro-2-(4-chloro-3-methylphenoxy)phenyl)-N-...)
Affinity DataIC50:  4.27nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246428(1-(4-chloro-2-(3,4-dichlorophenoxy)-5-fluorophenyl...)
Affinity DataIC50:  4.37nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246478(1-(2-(3,4-dichlorophenoxy)-5-fluoro-4-methoxypheny...)
Affinity DataIC50:  4.51nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246134(1-(4-chloro-2-(3,4-dimethylphenoxy)phenyl)-N-methy...)
Affinity DataIC50:  4.67nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246325(1-(5-bromo-2-(3,4-dichlorophenoxy)phenyl)-N-methyl...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246183(4-(3,4-dichlorophenoxy)-3-((dimethylamino)methyl)a...)
Affinity DataIC50:  4.99nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20966(2-Aryloxy-4-alkylaminopyridine, 3a | 3,6-dimethyl-...)
Affinity DataIC50:  5.10nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246324(1-(4-bromo-2-(3,4-dichlorophenoxy)phenyl)-N-methyl...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of binding of 70 pM [125I]-Try0-o-Corticotropin-releasing Factor (CFR) to Corticotropin releasing hormone receptor 1 in Rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20949(2-(4-chloro-2,6-dimethylphenoxy)-3,6-dimethyl-4-(p...)
Affinity DataIC50:  5.5nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246481(1-(2-(4-chloro-3-ethylphenoxy)-5-fluorophenyl)-N-m...)
Affinity DataIC50:  5.53nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20968(2-(4-bromo-2,6-dimethylphenoxy)-3,6-dimethyl-N-(pe...)
Affinity DataIC50:  5.60nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246535(1-(5-chloro-2-(3,4-dichlorophenoxy)phenyl)-N-methy...)
Affinity DataIC50:  5.73nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246278(1-(4-chloro-2-(3,4-dichlorophenoxy)phenyl)-N-methy...)
Affinity DataIC50:  6.22nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20969(2-Aryloxy-4-alkylaminopyridine, 5a | methyl 2-(4-c...)
Affinity DataIC50:  6.40nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246531(1-(4-chloro-2-(4-chlorophenoxy)phenyl)-N-methylmet...)
Affinity DataIC50:  6.59nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20933(3,6-dimethyl-4-(pentan-3-yloxy)-2-(2,4,6-trimethyl...)
Affinity DataIC50:  6.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20933(3,6-dimethyl-4-(pentan-3-yloxy)-2-(2,4,6-trimethyl...)
Affinity DataIC50:  6.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246533(1-(4-chloro-2-(3,4-dimethylphenoxy)phenyl)-N-methy...)
Affinity DataIC50:  6.82nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Pfizer

LigandPNGBDBM20967(2-(4-chloro-2,6-dimethylphenoxy)-3,6-dimethyl-N-(p...)
Affinity DataIC50:  7.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50246536(1-(5-chloro-2-(4-chlorophenoxy)phenyl)-N-methylmet...)
Affinity DataIC50:  7.49nMAssay Description:Inhibition of serotonin reuptake at SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 256 total ) | Next | Last >>
Jump to: