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Found 44 with Last Name = 'gaskin' and Initial = 'h'
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280074((Z)-6-{(2S,4S,5R)-2-[1-Methyl-1-(4-methyl-2-nitro-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280066((Z)-6-{(2S,4S,5R)-2-[1-Methyl-1-(4-methyl-2-nitro-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280723(CHEMBL175801 | {6-Fluoro-9-[3-(6-pyridin-3-yl-hex-...)
Affinity DataIC50:  40nMAssay Description:Human microsomal Thromboxane synthase inhibition was determined by inhibiting TXB2 formation from [14C]- labelled arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280073((Z)-6-{(2S,4S,5R)-4-(3-Methyl-3H-imidazol-4-yl)-2-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280719(CHEMBL175538 | {6-Fluoro-9-[3-(5-pyridin-3-yl-pent...)
Affinity DataIC50:  50nMAssay Description:Human microsomal Thromboxane synthase inhibition was determined by inhibiting TXB2 formation from [14C]- labelled arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280072((Z)-6-[(4S,5R)-2,2-Dimethyl-4-(3-methyl-3H-imidazo...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280063((Z)-6-((4S,5R)-2,2-Dimethyl-4-thiazol-5-yl-[1,3]di...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280720(CHEMBL425325 | {6-Fluoro-9-[3-(4-pyridin-3-yl-buto...)
Affinity DataIC50:  100nMAssay Description:Human microsomal Thromboxane synthase inhibition was determined by inhibiting TXB2 formation from [14C]- labelled arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280070((Z)-6-((4S,5R)-2,2-Dimethyl-4-pyridin-3-yl-[1,3]di...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280724(CHEMBL362418 | {6-Fluoro-9-[3-((Z)-5-pyridin-3-yl-...)
Affinity DataIC50:  200nMAssay Description:Human microsomal Thromboxane synthase inhibition was determined by inhibiting TXB2 formation from [14C]- labelled arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280721(CHEMBL174388 | {6-Fluoro-9-[3-(5-pyridin-3-yl-pent...)
Affinity DataIC50:  300nMAssay Description:Human microsomal Thromboxane synthase inhibition was determined by inhibiting TXB2 formation from [14C]- labelled arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280722(CHEMBL172198 | {6-Fluoro-9-[4-(6-pyridin-3-yl-hex-...)
Affinity DataIC50:  400nMAssay Description:Human microsomal Thromboxane synthase inhibition was determined by inhibiting TXB2 formation from [14C]- labelled arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280067((Z)-6-{(2S,4S,5R)-4-(3-Hexyl-3H-imidazol-4-yl)-2-[...)
Affinity DataIC50:  490nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280726(CHEMBL177596 | {6-Fluoro-9-[3-(5-pyridin-3-yl-pent...)
Affinity DataIC50:  500nMAssay Description:Human microsomal Thromboxane synthase inhibition was determined by inhibiting TXB2 formation from [14C]- labelled arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280725(CHEMBL427300 | {6-Fluoro-9-[4-(5-pyridin-3-yl-pent...)
Affinity DataIC50:  600nMAssay Description:Human microsomal Thromboxane synthase inhibition was determined by inhibiting TXB2 formation from [14C]- labelled arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280069((Z)-6-[(4S,5R)-4-(3-Hexyl-3H-imidazol-4-yl)-2,2-di...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280071((Z)-6-((4S,5R)-2,2-Dimethyl-4-thiophen-2-yl-[1,3]d...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280068((Z)-6-((4S,5R)-2,2-Dimethyl-4-pyridazin-4-yl-[1,3]...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280065((Z)-6-((4S,5R)-2,2-Dimethyl-4-pyrazin-2-yl-[1,3]di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280064((Z)-6-((4S,5R)-2,2-Dimethyl-4-oxazol-5-yl-[1,3]dio...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane-A synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280075((Z)-6-((4S,5R)-2,2-Dimethyl-4-pyrimidin-5-yl-[1,3]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165045(6-{3-Isopropoxy-5-[2-(tetrahydro-pyran-4-yl)-ethox...)
Affinity DataEC50:  1.33E+3nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165047(6-[3-Isopropoxy-5-(3-phenyl-propoxy)-benzoylamino]...)
Affinity DataEC50:  420nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165046(6-(2-Benzyloxy-benzoylamino)-nicotinic acid | CHEM...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165043(6-[3,5-Bis-(2-fluoro-benzyloxy)-benzoylamino]-nico...)
Affinity DataEC50:  90nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165044(6-(3-Cyclopentylmethoxy-5-isopropoxy-benzoylamino)...)
Affinity DataEC50:  650nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165042(6-(3,5-Dimethoxy-phenoxymethyl)-nicotinic acid | C...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165041(6-(3-(benzyloxy)-5-isopropoxybenzamido)nicotinic a...)
Affinity DataEC50:  290nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165039(6-[3-(2-Chloro-benzyloxy)-benzoylamino]-nicotinic ...)
Affinity DataEC50:  910nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165040(6-(3-Isopropoxy-5-phenethyloxy-benzoylamino)-nicot...)
Affinity DataEC50:  130nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165038(6-(3,5-Bis-benzyloxy-benzyloxy)-nicotinic acid | C...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165036(6-(3,5-Bis-benzyloxy-phenylcarbamoyl)-nicotinic ac...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165037(6-(3-Isobutoxy-5-isopropoxy-benzoylamino)-nicotini...)
Affinity DataEC50:  570nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165035(6-[3-(2-Fluoro-benzyloxy)-5-isopropoxy-benzoylamin...)
Affinity DataEC50:  100nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165033(6-[2,3-Bis-(2-chloro-benzyloxy)-benzoylamino]-nico...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165034(6-[3-Isopropoxy-5-(2-pyridin-4-yl-ethoxy)-benzoyla...)
Affinity DataEC50:  1.78E+3nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165032(6-(2-Benzyloxy-5-methylsulfanyl-phenylcarbamoyl)-n...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165031(6-({3-isopropoxy-5-[2-(3-thienyl)ethoxy]benzoyl}am...)
Affinity DataEC50:  90nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165030(6-(3,5-Bis-benzyloxy-benzoylamino)-nicotinic acid ...)
Affinity DataEC50:  400nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165029(6-[3-(2-Cyclopentyl-ethoxy)-5-isopropoxy-benzoylam...)
Affinity DataEC50:  170nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165027(6-[2-(3,5-Bis-benzyloxy-phenyl)-ethyl]-nicotinic a...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165028(6-[(E)-2-(2-Benzyloxy-5-methylsulfanyl-phenyl)-vin...)
Affinity DataEC50:  3.20E+3nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165025(6-[3-Isopropoxy-5-(2-pyridin-3-yl-ethoxy)-benzoyla...)
Affinity DataEC50:  1.26E+3nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50165026(6-(2-Benzyloxy-5-methylsulfanyl-benzoylamino)-nico...)
Affinity DataEC50:  4.22E+3nMAssay Description:Potency in Glucokinase activation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed