Found 60 with Last Name = 'gestwicki' and Initial = 'je' 
Affinity DataKi: 94nMAssay Description:Inhibition of wild-type HIV-1 protease using fluorogenic peptide substrate incubated for 30 mins prior to substrate addition measured after 10 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of multidrug resistant HIV-1 protease L10I/L63P/A71V/G73S/I84V/L90M mutant using fluorogenic peptide substrate incubated for 30 mins prior...More data for this Ligand-Target Pair
Affinity DataKi: 9.10E+4nMAssay Description:Inhibition of multidrug resistant HIV-1 protease L10I/L63P/A71V/G73S/I84V/L90M mutant using fluorogenic peptide substrate incubated for 30 mins prior...More data for this Ligand-Target Pair
Affinity DataKi: 9.60E+4nMAssay Description:Inhibition of wild-type HIV-1 protease using fluorogenic peptide substrate incubated for 30 mins prior to substrate addition measured after 10 mins b...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataIC50: <300nMAssay Description:Displacement of FITC-WFYpSPFLE from human Pin1 (45-163) catalytic domain by fluorescence polarization assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetHeat shock-related 70 kDa protein 2(Homo sapiens)
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of (2S,8S,11S,14S)-2-(4-aminobutyl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-(hydroxymethyl)-4,7,10,13,16,32-hexaoxo-36-((3aS,4S,6aR)...More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of FITC-WFYpSPFLE from human Pin1 (45-163) catalytic domain by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of FITC-WFYpSPFLE from human Pin1 (45-163) catalytic domain by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of FITC-WFYpSPFLE from human Pin1 (45-163) catalytic domain by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human HSF1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in HSF1 trimer-5-fluorescein labeled HSE interact...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
The University Of Kansas
Curated by ChEMBL
The University Of Kansas
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Hsp90 in human SkBr3 cells assessed as induction of Her2 degradation by ELISAMore data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human HSF1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in HSF1 trimer-5-fluorescein labeled HSE interact...More data for this Ligand-Target Pair
TargetHeat shock-related 70 kDa protein 2(Homo sapiens)
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of (2S,8S,11S,14S)-2-(4-aminobutyl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-(hydroxymethyl)-4,7,10,13,16,32-hexaoxo-36-((3aS,4S,6aR)...More data for this Ligand-Target Pair
TargetHeat shock-related 70 kDa protein 2(Homo sapiens)
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 8.73E+4nMAssay Description:Inhibition of (2S,8S,11S,14S)-2-(4-aminobutyl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-(hydroxymethyl)-4,7,10,13,16,32-hexaoxo-36-((3aS,4S,6aR)...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of recombinant human HSF1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in HSF1 trimer-5-fluorescein labeled HSE interact...More data for this Ligand-Target Pair
TargetHeat shock-related 70 kDa protein 2(Homo sapiens)
University Of New South Wales
Curated by ChEMBL
University Of New South Wales
Curated by ChEMBL
Affinity DataIC50: 2.48E+5nMAssay Description:Inhibition of (2S,8S,11S,14S)-2-(4-aminobutyl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-(hydroxymethyl)-4,7,10,13,16,32-hexaoxo-36-((3aS,4S,6aR)...More data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 7.70E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 1.90E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 1.50E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 2.30E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 1.09E+4nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 2.40E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 660nMAssay Description:Binding affinity to human HSC70 after 2 hrs by fluorescence shift assayMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to human HSC70 after 2 hrs by fluorescence shift assayMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 2.38E+3nMAssay Description:Binding affinity to human HSC70 Y149A mutant after 2 hrs by fluorescence shift assayMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 8.25E+3nMAssay Description:Binding affinity to human HSC70 T222A mutant after 2 hrs by fluorescence shift assayMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 1.38E+4nMAssay Description:Binding affinity to human HSC70 L228A mutant after 2 hrs by fluorescence shift assayMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 2.43E+4nMAssay Description:Binding affinity to human HSC70 H227A mutant after 2 hrs by fluorescence shift assayMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 5.54E+3nMAssay Description:Binding affinity to human HSC70 Y149W mutant after 2 hrs by fluorescence shift assayMore data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataEC50: >8.00E+3nMAssay Description:Binding affinity to recombinant human HSF1 monomer delta LZ1-3 mutant expressed in Escherichia coli BL21 (DE3) after 15 mins by fluorescence polariza...More data for this Ligand-Target Pair
TargetHeat shock factor protein 1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataEC50: 4.50E+3nMAssay Description:Binding affinity to recombinant human HSF1 monomer expressed in Escherichia coli BL21 (DE3) after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: 7.00E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: 1.60E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: 8.00E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: 4.70E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: 2.20E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: 6.80E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: 6.40E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: 6.30E+4nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: 1.77E+5nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetHeat shock protein beta-1(Homo sapiens (Human))
University Of California At San Francisco
Curated by ChEMBL
University Of California At San Francisco
Curated by ChEMBL
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to HSP27 (79 to 176 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells by HSQC NMR analysisMore data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase NIMA-interacting 1(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 72nMAssay Description:Binding affinity to full length Pin 1 (unknown origin) by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 4.00E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 1.70E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 2.60E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 900nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 400nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 5.40E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
TargetHeat shock cognate 71 kDa protein(Homo sapiens (Human))
University Of California San Francisco
Curated by ChEMBL
University Of California San Francisco
Curated by ChEMBL
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to human HSC70 after 3 hrs by ELISAMore data for this Ligand-Target Pair
