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Found 47 with Last Name = 'gibbs' and Initial = 'bs'
LigandPNGBDBM50060140(CHEMBL115943 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-cy...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060144(CHEMBL325073 | [(S)-1-{(4-Benzyloxy-benzyl)-[((R)-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060141(CHEMBL431440 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-me...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060145(CHEMBL115669 | [(S)-1-{(4-Benzyloxy-benzyl)-[((S)-...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060149(CHEMBL112512 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060139(CHEMBL326352 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060146(CHEMBL407445 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060138(CHEMBL324827 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060150(CHEMBL114281 | [(S)-1-{(4-Benzyloxy-benzyl)-[((R)-...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060142(CHEMBL326127 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)
Affinity DataIC50:  17nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060148(CHEMBL325331 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50081229(10-(tert-butyl)-2,6-dimethyl-(6E,10Z)-2,6,10-dodec...)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060152(CHEMBL112879 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-et...)
Affinity DataIC50:  32nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060143(CHEMBL324345 | [(S)-1-{(4-Benzyloxy-benzyl)-[((S)-...)
Affinity DataIC50:  41nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059857(CHEMBL102955 | [(S)-1-[(4-Benzyloxy-benzyl)-(phene...)
Affinity DataIC50:  62nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059876(CHEMBL217423 | [(S)-1-[(S)-1-{(S)-2-Benzyloxy-1-[(...)
Affinity DataIC50:  76nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060139(CHEMBL326352 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)
Affinity DataIC50:  88nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50081234(3-[(Z)-ethylidene]-7,11-dimethyl-(6E)-1,6,10-dodec...)
Affinity DataIC50:  173nMAssay Description:Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060141(CHEMBL431440 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-me...)
Affinity DataIC50:  180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060146(CHEMBL407445 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)
Affinity DataIC50:  180nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50081235(3-substituted farnesyl diphosphate analogue | 4-[(...)
Affinity DataIC50:  189nMAssay Description:Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060140(CHEMBL115943 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-cy...)
Affinity DataIC50:  190nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50081227(10-ethyl-2,6-dimethyl-(6E,10E)-2,6,10-dodecatriene...)
Affinity DataIC50:  215nMAssay Description:Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060151(CHEMBL408134 | [(S)-1-{(4-Benzyloxy-benzyl)-[(1,1-...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50081226(1-[1-[(Z)-ethylidene]-5,9-dimethyl-(4E)-4,8-decadi...)
Affinity DataIC50:  299nMAssay Description:Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060145(CHEMBL115669 | [(S)-1-{(4-Benzyloxy-benzyl)-[((S)-...)
Affinity DataIC50:  300nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060138(CHEMBL324827 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)
Affinity DataIC50:  310nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059879(CHEMBL102492 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-be...)
Affinity DataIC50:  320nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060142(CHEMBL326127 | [(S)-1-((4-Benzyloxy-benzyl)-{[(1-p...)
Affinity DataIC50:  330nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060149(CHEMBL112512 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)
Affinity DataIC50:  400nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50081238(4-[(Z)-ethylidene]-8,12,16-trimethyl-(7E,11E)-1,7,...)
Affinity DataIC50:  453nMAssay Description:Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060150(CHEMBL114281 | [(S)-1-{(4-Benzyloxy-benzyl)-[((R)-...)
Affinity DataIC50:  570nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060144(CHEMBL325073 | [(S)-1-{(4-Benzyloxy-benzyl)-[((R)-...)
Affinity DataIC50:  710nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50081233(3-[(Z)-ethylidene]-7,11,15-trimethyl-(6E,10E)-1,6,...)
Affinity DataIC50:  715nMAssay Description:Inhibition of recombinant farnesyltransferase (mFTase) in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060152(CHEMBL112879 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-et...)
Affinity DataIC50: >1.00E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060148(CHEMBL325331 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-ph...)
Affinity DataIC50: >1.00E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081233(3-[(Z)-ethylidene]-7,11,15-trimethyl-(6E,10E)-1,6,...)
Affinity DataIC50:  3.05E+3nMAssay Description:Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081238(4-[(Z)-ethylidene]-8,12,16-trimethyl-(7E,11E)-1,7,...)
Affinity DataIC50:  3.38E+3nMAssay Description:Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50060147(CHEMBL114495 | [(S)-1-{(4-Benzyloxy-benzyl)-[(meth...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro inhibition of rat farnesyltransferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059857(CHEMBL102955 | [(S)-1-[(4-Benzyloxy-benzyl)-(phene...)
Affinity DataIC50:  4.30E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50060143(CHEMBL324345 | [(S)-1-{(4-Benzyloxy-benzyl)-[((S)-...)
Affinity DataIC50:  6.30E+3nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGTPase HRas(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50059879(CHEMBL102492 | [(S)-1-{(4-Benzyloxy-benzyl)-[(2-be...)
Affinity DataIC50:  1.43E+4nMAssay Description:Concentration required to inhibit 50% of the cultured colonies of H-Ras-Fcells .More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081229(10-(tert-butyl)-2,6-dimethyl-(6E,10Z)-2,6,10-dodec...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081234(3-[(Z)-ethylidene]-7,11-dimethyl-(6E)-1,6,10-dodec...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081226(1-[1-[(Z)-ethylidene]-5,9-dimethyl-(4E)-4,8-decadi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081227(10-ethyl-2,6-dimethyl-(6E,10E)-2,6,10-dodecatriene...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50081235(3-substituted farnesyl diphosphate analogue | 4-[(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Geranylgeranyl transferase type I in scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed