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Found 76 with Last Name = 'höffken' and Initial = 'hw'
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182198(((R)-2-{(S)-2-[(5-carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  1nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  1nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182196(((R)-2-{(S)-5-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182194(CHEMBL206418 | {(R)-2-[(S)-2-(4-carbamimidoyl-benz...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182194(CHEMBL206418 | {(R)-2-[(S)-2-(4-carbamimidoyl-benz...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183868(((R)-2-{(S)-2-[(5-carbamimidoyl-4-methyl-thiophen-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182201(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183870(((R)-2-{(S)-2-[(4-carbamimidoyl-3-chloro-thiophen-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182189(CHEMBL207187 | {(R)-2-[(S)-2-(4-carbamimidoyl-benz...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183879(((R)-2-{(S)-2-[(4-carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182210(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182197(((R)-2-{(S)-5-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183872(((R)-2-{(S)-2-[(5-carbamimidoyl-4-chloro-thiophen-...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50129034(((R)-2-{(S)-2-[(5-Carbamimidoyl-1H-pyrrol-2-ylmeth...)
Affinity DataIC50:  6.20nMAssay Description:In vitro inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50129034(((R)-2-{(S)-2-[(5-Carbamimidoyl-1H-pyrrol-2-ylmeth...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183880(((R)-2-{(S)-2-[(5-carbamimidoyl-thiophen-3-ylmethy...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183878(((R)-2-{(S)-2-[(4-carbamimidoyl-3-methyl-thiophen-...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50129033(((R)-2-{(S)-2-[(5-Carbamimidoyl-1-methyl-1H-pyrrol...)
Affinity DataIC50:  11nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50129033(((R)-2-{(S)-2-[(5-Carbamimidoyl-1-methyl-1H-pyrrol...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Basf

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182208(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  14.8nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182190(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Basf

Curated by ChEMBL
LigandPNGBDBM50129034(((R)-2-{(S)-2-[(5-Carbamimidoyl-1H-pyrrol-2-ylmeth...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182207(CHEMBL208262 | N-(CARBOXYMETHYL)-3-CYCLOHEXYL-D-AL...)
Affinity DataIC50:  20.2nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183875(((R)-2-{(S)-2-[(4-carbamimidoyl-oxazol-2-ylmethyl)...)
Affinity DataIC50:  21nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182193(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  31.9nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183887(((R)-2-{(S)-2-[(3-carbamimidoyl-isoxazol-5-ylmethy...)
Affinity DataIC50:  34nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183888(((R)-2-{(S)-2-[(2-carbamimidoyl-thiazol-4-ylmethyl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182187(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  44.2nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182191(((R)-1-{1-[(6-carbamimidoyl-pyridin-3-ylmethyl)-ca...)
Affinity DataIC50:  47.3nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183866(((R)-2-{(S)-2-[(5-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50:  49nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183876(((R)-2-{(S)-2-[(5-carbamimidoyl-pyridin-2-ylmethyl...)
Affinity DataIC50:  51nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183869(((R)-2-{(S)-2-[(5-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  51nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182204(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  56.3nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183890(((R)-2-{(S)-2-[(5-amino-4-carbamimidoyl-thiophen-2...)
Affinity DataIC50:  57nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182211(((R)-2-{(R)-4-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  58.4nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  69nMAssay Description:In vitro inhibitory activity against thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  69nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM29388(Exanta | Melagatran | US11584714, Compound 999)
Affinity DataIC50:  69.2nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50114263(((R)-2-{(S)-2-[(5-Carbamimidoyl-thiophen-2-ylmethy...)
Affinity DataIC50:  70nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182206(((R)-2-{(S)-2-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  71.2nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182188(((R)-1-{(S)-1-[(6-carbamimidoyl-pyridin-3-ylmethyl...)
Affinity DataIC50:  76.8nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50182205(((R)-1-{1-[(6-carbamimidoyl-pyridin-3-ylmethyl)-ca...)
Affinity DataIC50:  103nMAssay Description:Inhibition of thrombin by chromogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183865(((R)-2-{(S)-2-[(4-carbamimidoyl-furan-2-ylmethyl)-...)
Affinity DataIC50:  125nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  173nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Abbott

Curated by ChEMBL
LigandPNGBDBM50183877(((R)-2-{(S)-2-[(4-carbamimidoyl-thiazol-2-ylmethyl...)
Affinity DataIC50:  201nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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