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Found 19 with Last Name = 'habeck' and Initial = 'll'
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288820((S)-2-{(S)-4-[4-(2,4-Diamino-pyrimidin-5-yl)-butyl...)
Affinity DataKi:  0.00500nMAssay Description:Binding affinity of the compound against Recombinant human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288821((S)-2-{(S)-4-[3-(2,4-Diamino-pyrimidin-5-yl)-propy...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity of the compound against Recombinant human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails Article
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50073754((R)-2-{4-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pyrido...)
Affinity DataKi:  0.290nMAssay Description:Inhibitory activity against recombinant human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50073752((R)-2-({5-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pyrid...)
Affinity DataKi:  0.690nMAssay Description:Inhibitory activity against recombinant human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50073753((R)-2-({5-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pyrid...)
Affinity DataKi:  9.90nMAssay Description:Inhibitory activity against recombinant human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM22590((2S)-2-[(4-{2-[(6R)-2-amino-4-oxo-1H,4H,5H,6H,7H,8...)
Affinity DataKi:  120nMAssay Description:Tested for the inhibition of trifunctional Glycinamide ribonucleotide formyltransferase isolated from murine L1210 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM22590((2S)-2-[(4-{2-[(6R)-2-amino-4-oxo-1H,4H,5H,6H,7H,8...)
Affinity DataKi:  130nMAssay Description:Tested for the inhibition of recombinant human monofunctional Glycinamide ribonucleotide formyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50073753((R)-2-({5-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pyrid...)
Affinity DataKi:  710nMAssay Description:Inhibitory activity against murine glycinamide ribonucleotide formyltransferase (GARFT) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073753((R)-2-({5-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pyrid...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory activity against recombinant human Thymidylate synthase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073752((R)-2-({5-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pyrid...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory activity against recombinant human Thymidylate synthase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50073754((R)-2-{4-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pyrido...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory activity against recombinant human Thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50288821((S)-2-{(S)-4-[3-(2,4-Diamino-pyrimidin-5-yl)-propy...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity of the compound against Recombinant human thymidylate synthase (TS)More data for this Ligand-Target Pair
In DepthDetails Article
TargetThymidylate synthase(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50288820((S)-2-{(S)-4-[4-(2,4-Diamino-pyrimidin-5-yl)-butyl...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity of the compound against Recombinant human thymidylate synthase (TS).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50073752((R)-2-({5-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pyrid...)
Affinity DataKi:  9.20E+3nMAssay Description:Inhibitory activity against murine glycinamide ribonucleotide formyltransferase (GARFT) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50281128((S)-2-{4-[2-(4-Oxo-3,4,5,6,7,8-hexahydro-pyrido[2,...)
Affinity DataKi:  2.70E+4nMAssay Description:Tested for the inhibition of trifunctional Glycinamide ribonucleotide formyltransferase isolated from murine L1210 cells.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50073754((R)-2-{4-[2-(2,4-Diamino-5,6,7,8-tetrahydro-pyrido...)
Affinity DataKi:  5.60E+4nMAssay Description:Inhibitory activity against murine glycinamide ribonucleotide formyltransferase (GARFT) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281128((S)-2-{4-[2-(4-Oxo-3,4,5,6,7,8-hexahydro-pyrido[2,...)
Affinity DataKi:  8.21E+4nMAssay Description:Tested for the inhibition of recombinant human monofunctional Glycinamide ribonucleotide formyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTrifunctional purine biosynthetic protein adenosine-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281129((S)-2-{4-[2-(2-Amino-5,6,7,8-tetrahydro-pyrido[2,3...)
Affinity DataKi:  1.86E+5nMAssay Description:Tested for the inhibition of recombinant human monofunctional Glycinamide ribonucleotide formyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281129((S)-2-{4-[2-(2-Amino-5,6,7,8-tetrahydro-pyrido[2,3...)
Affinity DataIC50:  65nMAssay Description:Tested for the inhibition against the human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails Article