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Found 64 with Last Name = 'hampannavar' and Initial = 'ga'
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232182(CHEMBL4097327)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]PK11195 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50087713((1-Ethyl-propyl)-[3-(4-methoxy-2-methyl-phenyl)-2,...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I-Tyr0]-CRF from recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232188(CHEMBL4070141)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Ro5-4864 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232179(CHEMBL4105538)
Affinity DataKi:  1.5nMAssay Description:Displacement of [125I-Tyr0]-CRF from recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232182(CHEMBL4097327)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]Ro5-4864 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232178(CHEMBL4081285)
Affinity DataKi:  1.70nMAssay Description:Displacement of [125I-Tyr0]-CRF from recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50116123(Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-pyr...)
Affinity DataKi:  2nMAssay Description:Displacement of 125I-sauvagine from CRF1 receptor in human IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50116095(CHEMBL293228 | [3-(2,4-Dichloro-phenyl)-2,5-dimeth...)
Affinity DataKi:  2nMAssay Description:Displacement of 125I-sauvagine from CRF1 receptor in human IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232188(CHEMBL4070141)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]PK11195 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232191(CHEMBL4089611)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]PK11195 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232191(CHEMBL4089611)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]Ro5-4864 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232201(CHEMBL4099753)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]Ro5-4864 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50116118(CHEMBL304272 | [3-(2,4-Dichloro-phenyl)-2,5-dimeth...)
Affinity DataKi:  3nMAssay Description:Displacement of 125I-sauvagine from CRF1 receptor in human IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50116093(CHEMBL304335 | [3-(2,4-Dichloro-phenyl)-2,5-dimeth...)
Affinity DataKi:  3nMAssay Description:Displacement of 125I-sauvagine from CRF1 receptor in human IMR-32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232190(CHEMBL4061482)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]Ro5-4864 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232201(CHEMBL4099753)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]PK11195 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232190(CHEMBL4061482)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]PK11195 from PBZR in rat kidney mitochondrial membranes measured after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232183(CHEMBL4097805)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]o-CRF from recombinant human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232200(CHEMBL4081736)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha1 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(RAT)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha5 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha1 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3(Rattus norvegicus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha3 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha2 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha1 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Affinity DataKi:  156nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha2 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3(Rattus norvegicus)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Affinity DataKi:  383nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha3 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(RAT)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232200(CHEMBL4081736)
Affinity DataKi:  740nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha5 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Rattus norvegicus (Rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232200(CHEMBL4081736)
Affinity DataKi:  927nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha2 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5(RAT)
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]RO15-1788 from recombinant rat GABAalpha5 receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM5413(1-(2-{4-[3-(thiophen-3-yl)pyrazolo[1,5-a]pyrimidin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM5409(4-(2-{4-[3-(thiophen-3-yl)pyrazolo[1,5-a]pyrimidin...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM5410(4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)ph...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454186(CHEMBL4215914)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to L298 residues)/CyclinE1 (M1 to A395 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50102311(3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human 143.98.2 cell derived COX2 assessed as reduction in PGE2 level using arachidonic acid as substrate pretreated for 15 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454183(CHEMBL4204229)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to L298 residues)/CyclinE1 (M1 to A395 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454185(CHEMBL4215776)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to L298 residues)/CyclinE1 (M1 to A395 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM5413(1-(2-{4-[3-(thiophen-3-yl)pyrazolo[1,5-a]pyrimidin...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrate by ECMAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232192(CHEMBL4082186)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM5409(4-(2-{4-[3-(thiophen-3-yl)pyrazolo[1,5-a]pyrimidin...)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrate by ECMAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50232184(CHEMBL4081227)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM5410(4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)ph...)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrate by ECMAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM5430(4-[3-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-6-y...)
Affinity DataIC50:  37nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50025724(CHEMBL175437 | N-(2-Dimethylamino-ethyl)-4-(1,3-di...)
Affinity DataIC50:  68nMAssay Description:Displacement of N6-[3H]Cyclohexyladenosine from adenosine A1 receptor in rat brain membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM5417(4-[6-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl]p...)
Affinity DataIC50:  224nMAssay Description:Inhibition of recombinant human GST-fused KDR kinase expressed in insect Sf21 cells using poly-Glu/Tyr (4:1) peptide as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50025699(5-(2-Amino-phenyl)-1,3-dimethyl-1,6-dihydro-pyrazo...)
Affinity DataIC50:  230nMAssay Description:Displacement of N6-[3H]Cyclohexyladenosine from adenosine A1 receptor in rat brain membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50025701(1-Ethyl-3-methyl-5-pyridin-4-yl-1,6-dihydro-pyrazo...)
Affinity DataIC50:  250nMAssay Description:Displacement of N6-[3H]Cyclohexyladenosine from adenosine A1 receptor in rat brain membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50132175(2-[(3-Isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-ylam...)
Affinity DataIC50:  440nMAssay Description:Inhibition of CDK1/CyclinB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454182(CHEMBL4210771)
Affinity DataIC50:  440nMAssay Description:Inhibition of recombinant human full length N-terminal GST/His6-tagged CDK5 (M1 to P292 residues)/N-terminal His6-tagged p25NCK (A104 to R307 residue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454182(CHEMBL4210771)
Affinity DataIC50:  990nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to M298 residues)/CyclinA2 (M1 to V432 residues) expressed in Sf9 insect c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
University Of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454182(CHEMBL4210771)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human full length N-terminal GST/His6-tagged CDK9 (M1 to F372 residues)/N-terminal His6-tagged CyclinT1 (M1 to K726 residue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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