Affinity DataKi: 16nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 140nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 150nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 290nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 350nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 380nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 680nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 720nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 750nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 880nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 950nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+3nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Binding affinity to human CXCR3 receptor expressed in CHO membrane by ITAC-stimulated GTP gammaS assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of rolipram binding to rat brain tissue at 20 uMMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of rolipram binding to rat brain tissue at 20 uMMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D
Curated by ChEMBL
Celltech R And D
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D
Curated by ChEMBL
Celltech R And D
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of rolipram binding to rat brain tissue at 20 uMMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of rolipram binding to rat brain tissue at 20 uMMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D
Curated by ChEMBL
Celltech R And D
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of rolipram binding to rat brain tissue at 20 uMMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D
Curated by ChEMBL
Celltech R And D
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory concentration against inosine-5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of rolipram binding in rat brain tissueMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D
Curated by ChEMBL
Celltech R And D
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of rolipram binding to PDE4 of rat brainMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rattus norvegicus)
Celltech-Chiroscience
Curated by ChEMBL
Celltech-Chiroscience
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of rolipram binding to rat brain tissue at 20 uMMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Celltech R And D
Curated by ChEMBL
Celltech R And D
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against IMPDH IIMore data for this Ligand-Target Pair