Affinity DataIC50: 1nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HSP90 in human A375 cells assessed as induction of HSP70 synthesis after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of HSP90-mediated pS6 phosphorylation in human A375 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as Hsp70 induction after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of HSP90-mediated Erk phosphorylation in human AU565 cells after 24 hrs by TRITC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as pERK degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
Affinity DataIC50: 50nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of Hsp90 in human A375 cells assessed as pS6 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
TargetTumor necrosis factor receptor superfamily member 10A(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Compound was tested for its ability to compete for binding to DR4 using ELISA assay.More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
Affinity DataIC50: 110nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 162nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 178nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 178nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 178nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
Affinity DataIC50: 190nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 293nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
Affinity DataIC50: 401nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
TargetHLA class II histocompatibility antigen, DR beta 3 chain(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 424nMAssay Description:Ability to compete for binding to Class II MHC using ELISA assay.More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of Hsp90 in human AU565 cells assessed as Her2 degradation after 24 hrs by high content screeningMore data for this Ligand-Target Pair
Affinity DataIC50: 498nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 568nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 50 uM ATP/[gamma-33P] ATP. 33P incorpor...More data for this Ligand-Target Pair
Affinity DataIC50: 665nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human SKBR3 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 705nMAssay Description:Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair