Compile Data Set for Download or QSAR
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Found 33 with Last Name = 'hanson' and Initial = 'sr'
TargetCoagulation factor VII(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  0.350nM ΔG°:  -53.4kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180400(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-...)
Affinity DataKi:  2nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM14898(2-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-5-(...)
Affinity DataKi:  4nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180405(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-ca...)
Affinity DataKi:  12nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180403(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-ca...)
Affinity DataKi:  12nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180404(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-(2...)
Affinity DataKi:  13nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180401(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-ca...)
Affinity DataKi:  14nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180406(2-[5'-aminomethyl-5-(5-carbamimidoyl-1H-benzoimida...)
Affinity DataKi:  35nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180407(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-5'-ca...)
Affinity DataKi:  43nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Celera Genomics

Curated by ChEMBL
LigandPNGBDBM50180402(2-[5-(5-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-...)
Affinity DataKi:  44nMAssay Description:Binding affinity to F7a/TF complexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  87nM ΔG°:  -39.9kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  114nM ΔG°:  -39.2kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi: >3.40E+3nM ΔG°: >-30.9kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi: >3.50E+3nM ΔG°: >-30.8kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  3.60E+3nM ΔG°:  -30.8kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi: >3.90E+3nM ΔG°: >-30.6kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
Genentech

LigandPNGBDBM14714((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...)
Affinity DataKi:  4.00E+3nM ΔG°:  -30.5kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylsulfatase(Pseudomonas aeruginosa)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50400985(CHEMBL2205724)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa aryl sulfatase after 20 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473488(CHEMBL141477)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473496(CHEMBL136246)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473487(CHEMBL336919)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473495(CHEMBL139282)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473493(CHEMBL138292)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473490(CHEMBL139200)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473494(Myoseverin)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473489(CHEMBL140649)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473492(CHEMBL140654)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
New York University

Curated by ChEMBL
LigandPNGBDBM50473491(CHEMBL343349)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of tubulin polymerization using bovine brain tubulinMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetArylsulfatase(Klebsiella pneumoniae)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50400983(CHEMBL2205726)
Affinity DataIC50:  8.00E+5nMAssay Description:Inhibition of Klebsiella pneumoniae aryl sulfatase after 0.5 hrs by para-nitrocatechol sulfate-based colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylsulfatase(Pseudomonas aeruginosa)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50400983(CHEMBL2205726)
Affinity DataIC50:  5.00E+6nMAssay Description:Inhibition of Pseudomonas aeruginosa aryl sulfatase after 0.5 hrs by para-nitrocatechol sulfate-based colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArylsulfatase(Klebsiella pneumoniae)
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50400984(CHEMBL2205725)
Affinity DataIC50:  1.00E+7nMAssay Description:Inhibition of Klebsiella pneumoniae aryl sulfatase after 20 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Bielefeld University

Curated by ChEMBL
LigandPNGBDBM50400983(CHEMBL2205726)
Affinity DataIC50:  1.50E+7nMAssay Description:Displacement of 3H-DHEAS from human steroid sulfatase after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed