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Found 54 with Last Name = 'hantschel' and Initial = 'o'
TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of MAP4K5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of YES1More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of ABL1More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of ABL2More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of FGRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of TAP-tagged wild-type BtkMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of FRKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of TNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of HCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSerine/threonine-protein kinase 24(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of STK24More data for this Ligand-Target Pair
TargetEphrin type-B receptor 2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant BtkMore data for this Ligand-Target Pair
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of EPHB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Blk(Mus musculus)
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of mouse BLKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of BMXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LYNAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of LYNBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTyrosine-protein kinase Blk(Mus musculus)
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse BLKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of MAP4K2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant Abl kinaseMore data for this Ligand-Target Pair
TargetMisshapen-like kinase 1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of MINK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of TRKAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of TRKBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 10(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  52nMAssay Description:Inhibition of STK10More data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  52nMAssay Description:Inhibition of SYKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  53nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  63nMAssay Description:Inhibition of CSKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  63nMAssay Description:Inhibition of PDGFRaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  92nMAssay Description:Inhibition of CAMK1DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  93nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  109nMAssay Description:Inhibition of RIPK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLIM domain kinase 1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  114nMAssay Description:Inhibition of LIMK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  134nMAssay Description:Inhibition of PTK2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  164nMAssay Description:Inhibition of cRAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  174nMAssay Description:Inhibition of AXLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  184nMAssay Description:Inhibition of CAMK2GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  191nMAssay Description:Inhibition of STK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  282nMAssay Description:Inhibition of TECMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  297nMAssay Description:Inhibition of recombinant Tec kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataIC50:  322nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fes/Fps(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  358nMAssay Description:Inhibition of FESMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  471nMAssay Description:Inhibition of TBK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fer(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50:  490nMAssay Description:Inhibition of FERMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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