Affinity DataKi: 5nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Binding affinity to human FLT3More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of semi-purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of semi-purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibitory activity was tested against human collagenase (MMP-1)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenase without beta-mercaptoethanolMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of semi-purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibitory activity was tested against human collagenase (MMP-1)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Potency of the compound at Endothelin A receptor was determinedMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of semi-purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of semi-purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibitory activity was tested against human collagenase (MMP-1)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of rat skin type I collagen degradation by purified human lung fibroblast collagenase without beta-mercaptoethanolMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Potency of the compound at Endothelin A receptor was determinedMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibitory activity was tested against human collagenase (MMP-1)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of degradation of radiolabeled rat skin type I collagen by semipurified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Potency of the compound at Endothelin A receptor was determinedMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of human fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibitory activity was tested against human collagenase (MMP-1)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 183nMAssay Description:Inhibition of semi-purified human lung fibroblast collagenaseMore data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of radiolabeled rat skin type I collagen degradation by purified human lung fibroblast collagenase.More data for this Ligand-Target Pair