Compile Data Set for Download or QSAR
maximum 50k data
Found 181 with Last Name = 'harries' and Initial = 'm'
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331382(CHEMBL1289063 | N-((3R,4R)-4-(4-(6-fluoropyridin-3...)
Affinity DataIC50:  80nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334942(1-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-in...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334936(CHEMBL1649665 | N-cyclopentyl-2-{4-[3-(trifluorome...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334935(1-{4-[1-(1-pyrrolidinylcarbonyl)cyclopropyl]phenyl...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331371(CHEMBL1290275 | N-((3R,4R)-4-(4'-cyanobiphenyl-4-y...)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50323798(CHEMBL1214336 | N-[5-(3-pyridinyl)-2,3-dihydro-1H-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human CYP1A2 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334936(CHEMBL1649665 | N-cyclopentyl-2-{4-[3-(trifluorome...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331373(CHEMBL1290391 | N-((3R,4R)-4-(4'-cyanobiphenyl-4-y...)
Affinity DataIC50:  800nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331381(CHEMBL1289062 | N-((3R,4R)-4-(4-(6-fluoropyridin-3...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334940(1-{4-[1-methyl-2-oxo-2-(1-pyrrolidinyl)ethyl]pheny...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334939(1-({4-[3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-i...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334948(CHEMBL1649654 | N-methyl-N-(2-phenylethyl)-4-[3-(t...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331369(CHEMBL1290165 | N-((3R,4R)-4-(3'-(methylsulfonamid...)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334937(1-({2-Fluoro-4-[3-(trifluoromethyl)-4,5,6,7-tetrah...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331370(CHEMBL1290166 | N-((3R,4R)-4-(4'-cyanobiphenyl-4-y...)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334947(CHEMBL1649655 | N,N-dimethyl-4-[3-(trifluoromethyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334949(1-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-in...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331367(CHEMBL1290058 | N-((3R,4R)-1-ethyl-4-(3'-(methylsu...)
Affinity DataIC50:  2.50E+3nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334946(1-{4-[2-OXO-2-(1-PYRROLIDINYL)ETHYL]PHENYL}-3-( TR...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334948(CHEMBL1649654 | N-methyl-N-(2-phenylethyl)-4-[3-(t...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334938(CHEMBL1649672 | N-({4-[3-(trifluoromethyl)-4,5,6,7...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331377(CHEMBL1290612 | N-((3R,4R)-1-methyl-4-(3'-(trifluo...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334941(1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-4...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334942(1-{4-[3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-in...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331384(CHEMBL1289180 | N-((3R,4R)-1-methyl-4-(4-(thiophen...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334945(1-{4-[1,1-difluoro-2-oxo-2-(1-pyrrolidinyl)ethyl]p...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334939(1-({4-[3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-i...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334935(1-{4-[1-(1-pyrrolidinylcarbonyl)cyclopropyl]phenyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334932(CHEMBL1649660 | N-butyl-N-methyl-4-[3-(trifluorome...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334943(1-[4-(1-Pyrrolidinylcarbonyl)phenyl]-3-(trifluorom...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334950(CHEMBL1594422 | N,N-Dimethyl-4-[3-(trifluoromethyl...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334941(1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-4...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334940(1-{4-[1-methyl-2-oxo-2-(1-pyrrolidinyl)ethyl]pheny...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331368(CHEMBL1290059 | N-((3R,4R)-1-isopropyl-4-(3'-(meth...)
Affinity DataIC50:  6.30E+3nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331380(CHEMBL1290732 | N-((3R,4R)-4-(4-(2-fluoropyridin-3...)
Affinity DataIC50:  6.30E+3nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334944(1-{3-Fluoro-4-[2-oxo-2-(1-pyrrolidinyl)ethyl]pheny...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334931(CHEMBL1649663 | N,N-Dimethyl-2-{4-[3-(trifluoromet...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334935(1-{4-[1-(1-pyrrolidinylcarbonyl)cyclopropyl]phenyl...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50331376(CHEMBL1290504 | N-((3R,4R)-4-(3'-acetylbiphenyl-4-...)
Affinity DataIC50:  7.90E+3nMAssay Description:Displacement of [3H]-dofetilide from human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334938(CHEMBL1649672 | N-({4-[3-(trifluoromethyl)-4,5,6,7...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP3A4 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334936(CHEMBL1649665 | N-cyclopentyl-2-{4-[3-(trifluorome...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP2C19 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334929(1-({4-[3-(Trifluoromethyl)-6,7-dihydropyrano[4,3-c...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of human CYP1A2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334932(CHEMBL1649660 | N-butyl-N-methyl-4-[3-(trifluorome...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50323794(CHEMBL1214396 | N-[5-(4-methyl-3-pyridinyl)-2,3-di...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human CYP3A4 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50334937(1-({2-Fluoro-4-[3-(trifluoromethyl)-4,5,6,7-tetrah...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human CYP2C9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Sussex

Curated by ChEMBL
LigandPNGBDBM50323797(CHEMBL1214337 | N-[5-(2-fluoro-3-pyridinyl)-2,3-di...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human CYP2C19 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 181 total ) | Next | Last >>
Jump to: