TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 112nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 167nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 175nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Displacement of FAM-labeled 5-GpYLPQTV-NH2 from recombinant GST-tagged STAT3 (unknown origin) preincubated for 30 mins followed by FAM-labeled 5-GpYL...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 282nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
South Valley University
Curated by ChEMBL
South Valley University
Curated by ChEMBL
Affinity DataIC50: 296nMAssay Description:Inhibition of VEGFR-2 (unknown origin) by using poly (Glu:Tyr 4:1) as substrate measured after 45 mins by Kinase-Glo max based microplate readerMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Displacement of FAM-labeled 5-GpYLPQTV-NH2 from recombinant GST-tagged STAT3 (unknown origin) preincubated for 30 mins followed by FAM-labeled 5-GpYL...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.08E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.22E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.89E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.92E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of STAT3 in human SB-590885-resistant 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of STAT3 in human SB-590885-sensitive 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
Affinity DataIC50: 7.17E+3nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of STAT3 in human SB-590885-sensitive 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of STAT3 in human SB-590885-resistant MEL1617 cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-sensitive MEL1617 cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-resistant MEL1617 cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-resistant 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+4nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.93E+4nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-sensitive MEL1617 cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-resistant MEL1617 cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 4.05E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-resistant 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-sensitive 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
The University Of Texas At Austin
Curated by ChEMBL
The University Of Texas At Austin
Curated by ChEMBL
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of STAT3 in human SB-590885-sensitive MEL1617 cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.72E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.12E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.12E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.49E+5nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.41E+6nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+6nMAssay Description:The assay mixture, containing 50 μl (2 mg/ml) of enzyme and 100 μl of different concentration of the tested agents, was added to 850 μ...More data for this Ligand-Target Pair