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Found 178 with Last Name = 'hayes' and Initial = 'jc'
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataKi:  5nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179460((R)-2-acetylamino-N-{(R)-1-benzyl-2-[(2S,4R)-4-ben...)
Affinity DataKi:  9nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179460((R)-2-acetylamino-N-{(R)-1-benzyl-2-[(2S,4R)-4-ben...)
Affinity DataKi:  10nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179468((S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataKi:  13nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179460((R)-2-acetylamino-N-{(R)-1-benzyl-2-[(2S,4R)-4-ben...)
Affinity DataKi:  23nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179467(CHEMBL381357 | Tic-D-Phe-Arg-2-Nal-NHCH3)
Affinity DataKi:  24nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179468((S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataKi:  30nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179461((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-phenyl...)
Affinity DataKi:  37nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179464(CHEMBL380437 | N-{3-[(2S,4R)-4-benzyloxy-1-((R)-2-...)
Affinity DataKi:  71nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179464(CHEMBL380437 | N-{3-[(2S,4R)-4-benzyloxy-1-((R)-2-...)
Affinity DataKi:  76nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  104nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179463((2R,5R)-5-acetylamino-2-benzyl-6-(4-hydroxy-phenyl...)
Affinity DataKi:  214nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179465((2R,5R)-5-acetylamino-6-(4-chloro-phenyl)-2-(4-flu...)
Affinity DataKi:  214nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179462((S)-2-((R)-2-benzyl-4-(R)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  220nMAssay Description:Binding affinity to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179464(CHEMBL380437 | N-{3-[(2S,4R)-4-benzyloxy-1-((R)-2-...)
Affinity DataKi:  382nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179468((S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataKi:  468nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179467(CHEMBL381357 | Tic-D-Phe-Arg-2-Nal-NHCH3)
Affinity DataKi:  1.63E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  1.73E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179467(CHEMBL381357 | Tic-D-Phe-Arg-2-Nal-NHCH3)
Affinity DataKi:  2.28E+3nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179462((S)-2-((R)-2-benzyl-4-(R)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  2.41E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179462((S)-2-((R)-2-benzyl-4-(R)-1,2,3,4-tetrahydro-isoqu...)
Affinity DataKi:  3.99E+3nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179459((S)-2-{(R)-2-[(S)-2-acetylamino-3-(4-hydroxy-pheny...)
Affinity DataKi:  4.52E+3nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataKi:  6.20E+3nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179463((2R,5R)-5-acetylamino-2-benzyl-6-(4-hydroxy-phenyl...)
Affinity DataKi:  8.56E+3nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179465((2R,5R)-5-acetylamino-6-(4-chloro-phenyl)-2-(4-flu...)
Affinity DataKi:  1.23E+4nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179465((2R,5R)-5-acetylamino-6-(4-chloro-phenyl)-2-(4-flu...)
Affinity DataKi:  1.80E+4nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179466((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-(4-hyd...)
Affinity DataKi:  2.23E+4nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179461((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-phenyl...)
Affinity DataKi:  2.34E+4nMAssay Description:Binding affinity to MC1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179463((2R,5R)-5-acetylamino-2-benzyl-6-(4-hydroxy-phenyl...)
Affinity DataKi:  2.47E+4nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50179461((2R,5R)-5-acetylamino-2-(4-fluoro-benzyl)-6-phenyl...)
Affinity DataKi:  5.55E+4nMAssay Description:Binding affinity to MC3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152280(CHEMBL364119 | Pyridine-2-carboxylic acid [(S)-1-(...)
Affinity DataEC50:  452nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152255(2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-2-(furan-2-ylami...)
Affinity DataEC50:  913nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152272(CHEMBL184466 | N-[(S)-1-((S)-1-{(S)-1-[(S)-1-Carba...)
Affinity DataEC50:  992nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152269(CHEMBL360598 | N-[1-((S)-(S)-1-{1-[(S)-(S)-1-Carba...)
Affinity DataEC50:  313nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152252((S)-2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-2-(5-phenyl-...)
Affinity DataEC50:  35nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152250((S)-2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-2-propionyla...)
Affinity DataEC50:  2.36E+3nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152282(2-{(S)-2-[(S)-2-Butyrylamino-3-(4-chloro-phenyl)-1...)
Affinity DataEC50:  827nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152249(5-Oxo-5-phenyl-pentanoic acid [1-((S)-(S)-1-{1-[(S...)
Affinity DataEC50:  41nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152288(CHEMBL187167 | N-[(S)-1-((S)-1-{(S)-1-[(S)-1-Carba...)
Affinity DataEC50:  1.01E+3nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152258((S)-2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-2-(2-cyano-a...)
Affinity DataEC50:  3.04E+3nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152251(CHEMBL434329 | N-[(S)-1-((S)-1-{(S)-1-[(S)-1-Carba...)
Affinity DataEC50:  164nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152256((S)-2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-2-(2-methoxy...)
Affinity DataEC50:  961nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152261((S)-2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-2-(2-hydroxy...)
Affinity DataEC50:  1.45E+3nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152275(2-{(S)-2-[(S)-2-But-3-enoylamino-3-(4-chloro-pheny...)
Affinity DataEC50:  863nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152278((S)-2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-2-(3-phenyl-...)
Affinity DataEC50:  170nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152281((S)-2-((S)-2-{(S)-3-(4-Chloro-phenyl)-2-[4-(4-fluo...)
Affinity DataEC50:  203nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152279(2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-1-oxo-2-phenylac...)
Affinity DataEC50:  43nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152266(2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-1-oxo-2-(4-pheny...)
Affinity DataEC50:  207nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152276((S)-2-{(S)-2-[(S)-2-(3-Allyl-ureido)-3-(4-chloro-p...)
Affinity DataEC50:  45nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152262((S)-2-{(S)-2-[(S)-3-(4-Chloro-phenyl)-2-methanesul...)
Affinity DataEC50:  6.70E+3nMAssay Description:Agonistic activity against against human Melanocortin 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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