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Found 1131 with Last Name = 'hehn' and Initial = 'jp'
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423171(US10501440, Example 3)
Affinity DataKi:  0.300nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423183(N-[(5R)-1-Amino-5H,6H,7H-cyclopenta[c]pyridin-5-yl...)
Affinity DataKi:  0.300nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423170(US10501440, Example 2)
Affinity DataKi:  0.300nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423169(N-[(5R)-1-Amino-5H,6H,7H-cyclopenta[c]pyridin-5-yl...)
Affinity DataKi:  0.300nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423179(N-[(5R)-1-Amino-5H,6H,7H-cyclopenta[c]pyridin-5-yl...)
Affinity DataKi:  0.400nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423174(US10501440, Example 5)
Affinity DataKi:  0.400nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423173(US10501440, Example 4)
Affinity DataKi:  0.400nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423180(N-[(5R)-1-Amino-3-methyl-5H,6H,7H-cyclopenta[c]pyr...)
Affinity DataKi:  0.400nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423185(N-[(5R)-1-Amino-3-methyl-5H,6H,7H-cyclopenta[c]pyr...)
Affinity DataKi:  0.400nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423187(N-[(5R)-1-Amino-3-methyl-5H,6H,7H-cyclopenta[c]pyr...)
Affinity DataKi:  0.5nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423188(N-[(5R)-1-Amino-3-methyl-5H,6H,7H-cyclopenta[c]pyr...)
Affinity DataKi:  0.5nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423182(US10501440, Example 12)
Affinity DataKi:  0.600nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423184(US10501440, Example 14)
Affinity DataKi:  1.10nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423181(US10501440, Example 11)
Affinity DataKi:  1.5nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423176(US10501440, Example 7)
Affinity DataKi:  1.90nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423186(N-[(5R)-1-Amino-5H,6H,7H-cyclopenta[c]pyridin-5-yl...)
Affinity DataKi:  2.20nMAssay Description:Human KLKB1 (1.78 nM or 0.025 U/mL; Enzyme Research Laboratories) was incubated at 24° C. with 0.25 mM fluorogenic substrate H-Pro-Phe-Arg-AMC (11295...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423170(US10501440, Example 2)
Affinity DataIC50:  0.300nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423180(N-[(5R)-1-Amino-3-methyl-5H,6H,7H-cyclopenta[c]pyr...)
Affinity DataIC50:  0.400nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423169(N-[(5R)-1-Amino-5H,6H,7H-cyclopenta[c]pyridin-5-yl...)
Affinity DataIC50:  0.5nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423183(N-[(5R)-1-Amino-5H,6H,7H-cyclopenta[c]pyridin-5-yl...)
Affinity DataIC50:  0.5nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423185(N-[(5R)-1-Amino-3-methyl-5H,6H,7H-cyclopenta[c]pyr...)
Affinity DataIC50:  0.5nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423179(N-[(5R)-1-Amino-5H,6H,7H-cyclopenta[c]pyridin-5-yl...)
Affinity DataIC50:  0.600nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423195(1-[2-Methyl-6-((1S,5R,6R)-6-methyl-3-aza-bicyclo[3...)
Affinity DataIC50:  0.600nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423171(US10501440, Example 3)
Affinity DataIC50:  0.700nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423173(US10501440, Example 4)
Affinity DataIC50:  0.800nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasma kallikrein(Rattus norvegicus)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM423174(US10501440, Example 5)
Affinity DataIC50:  0.800nMAssay Description:Human KLKB1 (0.01 U/mL; Enzyme Research Laboratories) or rat KLKB1 (0.625 nM; produced in-house) was incubated for 1 h at room temperature with 0.10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181457(US9139577, 3.018 | US9708274, 3.018)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181478(US9139577, 3.039 | US9708274, 3.039)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181486(US9139577, 3.047 | US9708274, 3.047)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181493(US9139577, 3.054 | US9708274, 3.054)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181521(US9139577, 4.027 | US9708274, 4.027)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181530(US9139577, 4.036 | US9708274, 4.036)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181533(US9139577, 4.039 | US9708274, 4.039)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181536(US9139577, 4.042 | US9708274, 4.042)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181544(US9139577, 4.050 | US9708274, 4.050)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181565(US9139577, 4.071 | US9708274, 4.071)
Affinity DataIC50:  1nMT: 2°CAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181390(US9139577, 1.021 | US9708274, 1.021)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181397(US9139577, 2.005 | US9708274, 2.005)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181400(US9139577, 2.008 | US9708274, 2.008)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181401(US9139577, 2.009 | US9708274, 2.009)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181408(US9139577, 2.016 | US9708274, 2.016)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181410(US9139577, 2.018 | US9708274, 2.018)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181411(US9139577, 2.019 | US9708274, 2.019)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181418(US9139577, 2.026 | US9708274, 2.026)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181423(US9139577, 2.032 | US9708274, 2.032)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181425(US9139577, 2.034 | US9708274, 2.034)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181432(US9139577, 2.041 | US9708274, 2.041)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181435(US9139577, 2.044 | US9708274, 2.044)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181436(US9139577, 2.045 | US9708274, 2.045)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM181444(US9139577, 3.005 | US9708274, 3.005)
Affinity DataIC50:  1nMAssay Description:The inhibition of kinase activity of MNK2a was assessed using pre-activated GST-MNK2a. The white, 384-well OptiPlate F plates were purchased from Per...More data for this Ligand-Target Pair
In DepthDetails US Patent
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